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临床试验/NCT03816215
NCT03816215已完成不适用

Volunteering as an Intervention to Reduce Depression Among Adolescents: Investigating Neurobiological Mechanisms

Wake Forest University Health Sciences6 个研究点 分布在 1 个国家目标入组 9 人开始时间: 2019年6月3日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
9
试验地点
6
主要终点
Participant recruitment

研究概览

简要总结

The purpose of the present study is to test in a preliminary manner an innovative strategy for treating depression among adolescents (alongside existing therapy) using community volunteerism.

详细描述

The purpose of the present study is to test in a preliminary manner an innovative strategy for treating depression among adolescents (alongside existing therapy) using community volunteerism. In addition, this study will test a potential mechanism by which volunteering might decrease depressive symptoms: increasing psychosocial assets, specifically decreasing self-orientation and increasing an orientation toward others. This will be measured through self-report as well as using functional magnetic resonance imaging (fMRI). This study will be the first study to explore how neural response patterns are potentially altered by intense experiences with volunteerism among depressed adolescents.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Treatment
盲法
None

入排标准

年龄范围
14 Years 至 20 Years(Child, Adult)
性别
All
接受健康志愿者

入选标准

  • age 14-20
  • new mild to moderate depression diagnosis (single episode)
  • new mild to moderate anxiety diagnosis
  • new adjustment disorder diagnosis
  • have been in treatment for < 8 months
  • right-handed

排除标准

  • history of recurrent depressive, anxiety or adjustment disorder episodes
  • have been in treatment > 8 months
  • left-handed
  • expressing suicidal ideation
  • claustrophobia
  • any contraindications for completing an MRI scan

结局指标

主要结局

Participant recruitment

时间窗: 6 months

Number of participants screened (reported by clinical mental health providers)

Participant retention

时间窗: 6 months

Number of participants retained in full study

Depressive symptoms (Beck Depression Inventory)

时间窗: 6 months

Beck Depression Inventory to measure depressive symptoms. Each item is rated on a 4-point scale ranging from 0 to 3. The minimum total score is 0 and the maximum total score is 63. Higher scores denote worse outcome

次要结局

  • Self-efficacy(6 months)
  • Empathy(6 months)
  • Strength of Connectivity in DMN (Default Mode Network)(6 months)
  • Hope scale (Abler et al., 2017)(6 months)
  • Beck Hopelessness Inventory(6 months)
  • Orientation Toward Others(6 months)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (6)

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