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Clinical Trials/NCT03816215
NCT03816215
Completed
Not Applicable

Volunteering as an Intervention to Reduce Depression Among Adolescents: Investigating Neurobiological Mechanisms

Wake Forest University Health Sciences3 sites in 1 country9 target enrollmentJune 3, 2019

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Depressive Symptoms
Sponsor
Wake Forest University Health Sciences
Enrollment
9
Locations
3
Primary Endpoint
Participant recruitment
Status
Completed
Last Updated
5 years ago

Overview

Brief Summary

The purpose of the present study is to test in a preliminary manner an innovative strategy for treating depression among adolescents (alongside existing therapy) using community volunteerism.

Detailed Description

The purpose of the present study is to test in a preliminary manner an innovative strategy for treating depression among adolescents (alongside existing therapy) using community volunteerism. In addition, this study will test a potential mechanism by which volunteering might decrease depressive symptoms: increasing psychosocial assets, specifically decreasing self-orientation and increasing an orientation toward others. This will be measured through self-report as well as using functional magnetic resonance imaging (fMRI). This study will be the first study to explore how neural response patterns are potentially altered by intense experiences with volunteerism among depressed adolescents.

Registry
clinicaltrials.gov
Start Date
June 3, 2019
End Date
August 1, 2020
Last Updated
5 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • age 14-20
  • new mild to moderate depression diagnosis (single episode)
  • new mild to moderate anxiety diagnosis
  • new adjustment disorder diagnosis
  • have been in treatment for \< 8 months
  • right-handed

Exclusion Criteria

  • history of recurrent depressive, anxiety or adjustment disorder episodes
  • have been in treatment \> 8 months
  • left-handed
  • expressing suicidal ideation
  • claustrophobia
  • any contraindications for completing an MRI scan

Outcomes

Primary Outcomes

Participant recruitment

Time Frame: 6 months

Number of participants screened (reported by clinical mental health providers)

Participant retention

Time Frame: 6 months

Number of participants retained in full study

Depressive symptoms (Beck Depression Inventory)

Time Frame: 6 months

Beck Depression Inventory to measure depressive symptoms. Each item is rated on a 4-point scale ranging from 0 to 3. The minimum total score is 0 and the maximum total score is 63. Higher scores denote worse outcome

Secondary Outcomes

  • Self-efficacy(6 months)
  • Empathy(6 months)
  • Strength of Connectivity in DMN (Default Mode Network)(6 months)
  • Hope scale (Abler et al., 2017)(6 months)
  • Beck Hopelessness Inventory(6 months)
  • Orientation Toward Others(6 months)

Study Sites (3)

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