Treatment of severe acute malnutrition delivered by Community Health Workers in Niger

Not Applicable

Completed

• Conditions: Severe acute malnutrition; Nutritional, Metabolic, Endocrine; Severe acute malnutrition (SAM)

• Registration Number: ISRCTN31143316
• Lead Sponsor: Action against Hunger

Brief Summary

2021 Results article in https://pubmed.ncbi.nlm.nih.gov/34836322/ (added 05/09/2022) 2024 Other publications in https://pubmed.ncbi.nlm.nih.gov/38553707/ (added 03/04/2024)

Detailed Description

Not available

Study Timeline

• Study Start: 2018-08-03
• Study Completion: 2019-08-01
• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 2789

Inclusion Criteria

1. Age 6 to 59 months
2. Diagnosed with SAM according to any of the following criteria:
2.1. MUAC < 115 mm
2.2. Bilateral edema
2.3. Weight-to-height ratio < -3 Z-score
3. Parents or guardians can provide informed consent

Exclusion Criteria

1. Residence outside the study areas
2. Complications that require treatment in the stabilization center in Mayahi

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The following performance indicators will be measured using the clinical and individual data obtained from ongoing care for the patients through the reporting system and procedures, including the children monitoring cards:<br>1. Cure rate, assessed at every visit to the healthy facility or with the CHW (weekly basis), defined as:<br>1.1. Weight-to-height ratio > 1.5<br>1.2. MUAC (mid-upper arm circumference) > 125 cm<br>2. Death rate, determined over the course of the study<br>3. Defaulter rate - if children do not attend visits on 2 consecutive weeks, they are discharged as defaulters

Secondary Outcome Measures

Name	Time	Method
Coverage of the interventions is measured using coverage assessment using the SQUEAC methodology (Semi-Quantitative Evaluation of Access and Coverage) in both areas at the baseline and at the end of the study. SQUEAC uses the following 3 stages:<br>1. Identification of low or high coverage areas, along with factors negatively influencing coverage by using routine data for the program and qualitative data gathered from key informers, with the goal of ensuring triangulation and exhaustiveness of sources and methods<br>2. Confirmation of low and high coverage areas, and of the factors explaining low coverage identified in stage 1<br>3. Estimation of program coverage using the Bayesian technique