A PROSPECTIVE STUDY TO EVALUATE THE EFFICACY AND SAFETY OF AN AYURVEDIC FORMULATION - URAL CAPSULE IN THE TREATMENT OF UROLITHIASIS

Stone formation in kidney is one of the oldest and the mostwidespread medical afflictions known to humans. It is a most common urinarytract problem all over the world, having prevalence rate of 2.3%. Patientsbetween ages of 20-50 years have peak incidence of stone formation. In India,6-8% population suffers from kidney stone. Ural Capsule is a patent &proprietary Ayurvedic formulation, recommended for treatment of urolithiasis.Previous experimental data has confirmed its safety and efficacy. Hence thepresent study is to be initiated to evaluate its clinical safety and efficacy.Open labelled, interventional clinical trial protocol has been designed toevaluate efficacy and safety of Ural Capsule in treatment of urolithiasis.Inclusion and exclusion criteria have been mentioned in protocol for selectionof patients. All selected patients will be treated with Ural Capsule for 3months (12 Weeks). For the assessment of efficacy different clinical parameterssuch as subjective parameters, Blood urea, Serum uric acid, Serum creatinine,X-ray (KUB) & Ultrasonography (KUB) will be considered. Routinehaematological parameters, routine urine analysis and routine stool analysiswill be done to evaluate safety of the drug. Follow-up visit will be scheduled at1 month interval after compilation of treatment up to 2 months. Appropriatestatistic will be applied to find out statistical significance level.

KeyWords : Ashmari,Urolithiasis, Kidney stones, Uralcapsule**.**