The added value of frequent intestinal ultrasonography in the close monitoring of moderate-severe ulcerative colitis
Completed
- Conditions
- Ulcerative colitis: inflammatory bowel (colon) disease1001796910003816
- Registration Number
- NL-OMON49013
- Lead Sponsor
- Academisch Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 54
Inclusion Criteria
*Ulcerative colitis, histologically and endoscopically confirmed
*Endoscopically moderate to severe disease with a eMayo score *2
*Start of medical treatment
*>18 years of age
Exclusion Criteria
*Age<18years
*Proctitis only
*Colonic stricture at baseline endoscopy
*Imminent need of surgery
*Sigmoidoscopy/colonoscopy older than eight weeks
*Ongoing gastroenteritis
*Cytomegalovirus (CMV) associated colitis
*Obesity (BMI >35 kg/m²)
*A normal bowel wall < 2mm at baseline ultrasonography
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The main endpoint of this study will be difference in change of bowel wall<br /><br>width within 26 weeks between the responding and non-responding group.</p><br>
- Secondary Outcome Measures
Name Time Method