Fecal microbiota transplantation for recurrent Clostridioides difficile infectio
Not Applicable
- Conditions
- Recurrent Clostridioides difficile infection
- Registration Number
- JPRN-UMIN000042418
- Lead Sponsor
- Shiga University of Medical Science
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 0
Inclusion Criteria
Not provided
Exclusion Criteria
(1) Those who cannot obtain appropriate donors (2) Immunosuppressive drugs (anti-cancer drugs, high-dose steroids (15 mg/day or more), calcineurin inhibitors, mTOR inhibitors, anti-TNF-a antibody, biologics that cause lynmphopenia (rituximab, anti-human thymocyte rabbit immunoglobulin etc.) (3) HIV virus infection (4) Decompensated cirrhosis (5) Pregnant women (6) Antibiotics other than recurrent Clostridioides difficile infection (7) Patients who cannot tolerate colonoscopy (8)Lymphocyte count(<750/mm3) (9)IgG(<500mg/dL) (10) Otherwise, if the attending doctor deems inappropriate
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Response rate of single FMT to recurrent CDI A response is a condition in which there is no recurrence. Recurrence is defined as diarrhea (at least three loose or watery stools per day for two or more consecutive days) and positivity in the CD toxin stool test or positivity for Clostridioides difficile in the stool culture and presence of pseudomembrane.
- Secondary Outcome Measures
Name Time Method