Transcranial Magnetic Stimulation for Borderline Personality Disorder

Not Applicable

Completed

• Conditions: Borderline Personality Disorder
• Interventions: Procedure: repetitive Transcranial Stimulation Magnetic (rTMS); Procedure: sham rTMS

• Registration Number: NCT01076933
• Lead Sponsor: University Hospital, Toulouse

Brief Summary

Primary purpose : to assess the effect on neuropsychological tasks related to planning of 10 daily sessions of right dorsolateral prefrontal cortex with High-frequency repetitive transcranial magnetic stimulation (rTMS) on borderline personality disorder (BPD) patients.

Hypothesis : BPD patients receiving 10 sessions of rTMS will have greater improvement in the average number of move to achieve tasks of the Tower of London, than those receiving sham rTMS.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-01
• Study First Submitted: 2010-01-06
• Study First Submitted QC: 2010-02-25
• Study First Posted: 2010-02-26
• Primary Completion: 2011-03
• Study Completion: 2012-04
• Status Verified: 2017-05
• Last Update Submitted: 2017-05-10
• Last Update Posted: 2017-05-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 13

Inclusion Criteria

• 20 to 45 years old
• Borderline Personality Disorder (Diagnostic Interview for Borderline Personality Disorder > 8)
• psychiatric follow-up
• righthander
• informed consent
• affiliated to medical insurance

Exclusion Criteria

• bipolar disorder
• substance use disorder
• Major Depressive Disorder or Stress Post Traumatic Disorder
• history of epilepsy
• neurosurgery
• cardiac pacemaker
• lefthander
• involuntary admission
• participation in an other research
• legal guardianship
• poor mastery of french.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
rTMS	repetitive Transcranial Stimulation Magnetic (rTMS)	rTMS sessions
control	sham rTMS	sham rTMS (control)

Primary Outcome Measures

Name	Time	Method
Tower of London	Inclusion, 15th day, 30th day and 3rd month

Secondary Outcome Measures

Name	Time	Method
Balloon Analog Risk Task	Inclusion, 15th day, 30th day and 3rd month
Micro-World Test	Inclusion, 15th day and 3rd month
Borderline Personality Disorder Severity Index	Pre-inclusion, 30th day and 3rd month
Symptom Check List - 90	Inclusion, 15th day, 30th day and 3rd month
Barratt Impulsivity Scale	Inclusion and 3rd month
Global Assessment Scale	Inclusion and 3rd month

Trial Locations

Locations (1)

Lionel Cailhol; 🇫🇷 Toulouse, University Hospital Toulouse, France