Oral dexamethasone as an adjunct to a brachial plexus block in patients undergoing orthopaedic surgery of the forearm and hand. A randomised, blinded, placebo-controlled, parallel, triple-arm clinical trial.

Zealand University Hospital, Department of Anaesthesiology0 个研究点目标入组 180 人开始时间: 2021年4月16日最近更新: 2021年5月17日

试验速览

暂无简介。

•Scheduled unilateral osseous surgery of the forearm or hand.
•Anaesthesia with a lateral infraclavicular brachial plexus block.
•Age of 18 or above.
•American Society of Anaesthesiologists Physical Status Score of 1 to 3.
•For fertile women, negative urine humane choriongonadotropine test or use of safe anti-conception.
•Ability to understand the trial protocol, risks and benefits, and provide signed informed consent.
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range 90
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range 90

•Participation in another trial involving medication.
•Allergy to study medication.
•Daily use of opioids above 30 mg/day morphine or equivalents.
•Daily use of corticosterioids of more than 5 mg prednisolone equivalents within the past one month.
•Neurological or musculoskeletal disease making block performance impossible.
•Dysregulated diabetes (as judged by the investigator).
•Dysregulated anticoagulants (as judged by the investigator).
•History of drug or alcohol abuse.
•Contraindications for paracetamol or opioids.
•Other concomitant conditions needing surgery.
•Other concomitant traumatic injuries.

发起方

Zealand University Hospital, Department of Anaesthesiology