Prediction of Postoperative Pain by Injection Pain of Propofol

• Conditions: Cholecystitis, Acute

• Registration Number: NCT03021447
• Lead Sponsor: Ajou University School of Medicine

Brief Summary

Postoperative pain is a significant postoperative problem and it could be persistent if proper management is not provided. However, each patient shows different intensity of pain and different sensitivity to analgesics even if they underwent same procedures. Therefore, it would be useful to find the way to predict the postoperative pain sensitivity.

Propofol, a popular anesthetic agent, induces pain during injection, which can not completely prevented by opioid or lidocaine in some patients. This is considered to be related to patient's pain sensitivity and it might be associated with postoperative pain sensitivity.

Therefore, the relation of propofol injection pain and postoperative pain intensity will be explored.

Detailed Description

Not available

Study Timeline

• Status Verified: 2017-01
• Study Start: 2017-01
• Study First Submitted: 2017-01-12
• Study First Submitted QC: 2017-01-13
• Last Update Submitted: 2017-01-13
• Study First Posted: 2017-01-16
• Last Update Posted: 2017-01-16
• Primary Completion: 2017-12
• Study Completion: 2017-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 70

Inclusion Criteria

• America Society of Anesthesiologists class I-II
• Laparoscopic cholecystectomy

Exclusion Criteria

• Pregnancy
• Illiteracy

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
postoperative pain intensity_1	10 min after postanesthesia care unit admission	Postoperative pain will be evaluated with verbal numeric scale (0-10)

Secondary Outcome Measures

Name	Time	Method
postoperative pain intensity_2	20 min after postanesthesia care unit admission	Postoperative pain will be evaluated with verbal numeric scale (0-10)
postoperative pain intensity_12	12 hours after operation	Postoperative pain will be evaluated with verbal numeric scale (0-10)
postoperative pain intensity_24	24 hours after operation	Postoperative pain will be evaluated with verbal numeric scale (0-10)
postoperative pain intensity_8	8 hours after operation	Postoperative pain will be evaluated with verbal numeric scale (0-10)
postoperative pain intensity_3	30 min after postanesthesia care unit admission	Postoperative pain will be evaluated with verbal numeric scale (0-10)
postoperative pain intensity_4	4 hours after operation	Postoperative pain will be evaluated with verbal numeric scale (0-10)