Validation, for Orbital Tumors, of the MRI Perfusion Curves Typology Established for Salivary Tumors
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 238
- 试验地点
- 1
- 主要终点
- Concordance of the MRI type and the pathological findings as assessed by the kappa coefficient
研究概览
简要总结
Orbital masses develop at the expense of the orbital structures lacrimal glands, oculomotor muscles, optic nerve, meningeal spaces, peripheral nerves, bone wall, orbital fat, lymphoid structures or vascular structures. These masses can be tumors, benign or malignant, or pseudotumor, mainly represented by specific or non-specific orbital inflammation.
Pathology is of considerable importance for the diagnosis and the treatment of those masses. However, biopsy or surgical resection of the orbital masses is sometimes difficult and dangerous outside expert centers.
The identification of a non-invasive technique for distinguishing tumors from pseudotumors, thus avoid in some cases a biopsy, would be a major contribution for the patients.
For salivary glands, MRI allows to identify 4 different types of MRI characteristics, one (type C) being related to malignant tumors.
In this study, the investigators will try to see if extrapolation of those data to orbiltal tumors is feasible.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient aged 18 years or more
- •with orbital mass for which a biopsy and/or a surgical removal is planned
- •undergoing an MRI
- •before surgery
排除标准
- •contra-indication to MRI
- •intolerance to constrast agent
- •pregnancy
- •breast feeding
- •patient under a legal protection procedure
- •patient denying to participate to the study
- •lack of affiliation to a social security system
结局指标
主要结局
Concordance of the MRI type and the pathological findings as assessed by the kappa coefficient
时间窗: one month
次要结局
未报告次要终点
