临床试验/NCT03411109

NCT03411109已完成不适用

Efficacy and Outcomes of Intrathecal Analgesia As Part of an Enhanced Recovery Pathway in Colon and Rectal Surgical Patients

Mayo Clinic1 个研究点分布在 1 个国家目标入组 601 人开始时间: 2012年10月1日最近更新: 2018年1月25日

适应症

干预措施

试验速览

阶段: 不适用
状态: 已完成
发起方: Mayo Clinic
入组人数: 601
试验地点: 1
主要终点: Time to return of bowel function

研究概览研究设计入排标准研究组 & 干预措施结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

Multimodal analgesia, sometimes including intrathecal analgesia (IA), is essential in any enhanced recovery pathway (ERP). This study aimed to evaluate the safety, feasibility, and optimal IA regimen in colorectal surgical patients.

研究设计

研究类型: Observational
观察模型: Cohort
时间视角: Retrospective

入排标准

年龄范围: 18 Years 至 —（Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•All adult colorectal patients from October 2012 through December 2013 in which patients received single-injection IA as part of a multimodal analgesic strategy for ERP.
•Undergoing an elective colorectal operation (minimally invasive or open)

排除标准

•Patients aged < 18 years
•American Society of Anesthesiologists (ASA) 5 and 6 classification
•pregnancy
•failure to provide research authorization.
•emergent operations

研究组 & 干预措施

Opioid Only Intrathecal

干预措施: Hydromorphone Hydrochloride (Drug)

Opioid + Local Anesthetic Intrathecal

干预措施: Hydromorphone Hydrochloride (Drug)

结局指标

主要结局

Time to return of bowel function

时间窗: post resection, approximately up to 48 hours

Time to return of bowel function is defined by the presence of flatus and a bowel movement

次要结局

未报告次要终点

研究者

发起方

Mayo Clinic

申办方类型

Other

责任方

Principal Investigator

主要研究者

Adam K. Jacob

Principal Investigator

Mayo Clinic

研究点 (1)

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