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Steroid induction regimen for juvenile idiopathic arthritis

Not Applicable
Completed
Conditions
Juvenile idiopathic arthritis
Musculoskeletal Diseases
Juvenile arthritis
Registration Number
ISRCTN16649996
Lead Sponsor
Alder Hey Children’s Foundation NHS Trust (UK)
Brief Summary

2020 results in https://pubmed.ncbi.nlm.nih.gov/32758350/(added 10/08/2020)

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
297
Inclusion Criteria

Patients with JIA and their parents/carers will be eligible to take part in the qualitative research aspect of the trial

Exclusion Criteria

Patients aged under 8 years and patients/carers residing more that one days' travel away from the primary research site (Liverpool)

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Develop outcomes of the feasibility study including a report to HTA with assessment of the proposed intervention and control arms for definitive study
Secondary Outcome Measures
NameTimeMethod
<br> 1. A comprehensive assessment of current UK practice as regards JIA CS treatment, and potential trial capability and acceptability (by conducting a national survey)<br> 2. Ascertainment of HCP views on the most appropriate patient group(s) and control and intervention arms (through a stakeholder consensus meeting)<br> 3. A qualitative study of parent and patient perspectives in relation to a future RCT of CS<br> 4. The choice of a primary outcome measure for a clinical trial in children and young people with JIA (through literature review, Delphi process and stakeholder consensus meeting)<br> 5. Undertake a prospective feasibility study for the early induction of remission in children and young people with JIA testing chosen primary outcome, treatment arms and JIA subgroups to be studied<br>
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