Randomised, placebo-controlled trial to assess the role of early prednisolone on the development and progression of Henoch Schonlein purpura nephritis

niversity Hospital of Wales NHS Trust (UK)0 个研究点目标入组 368 人开始时间: 2011年11月30日最近更新: 2015年1月13日

适应症

试验速览

暂无简介。

•Children under 18 years of age presenting to secondary care centres in England and Wales with a diagnosis of Henoch-Schönlein Purpura (HSP), based on the American College of Rheumatology Criteria

•1. Those already receiving steroid / immunosuppressive therapy
•2. Those receiving Angiotensin converting enzyme (ACE) inhibitors
•3. Those with pre-existing renal disease (excluding urinary tract infections)
•4. Those with pre-existing hypertension
•5. Those with evidence of immunodeficiency /systemic infection
•6. Those with contra-indications or relative contra-indications for steroid therapy (epilepsy, diabetes mellitus, glaucoma or peptic ulceration)
•7. Those with characteristic purpuric rash for more than 7 days

发起方

niversity Hospital of Wales NHS Trust (UK)