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临床试验/NCT04880265
NCT04880265招募中不适用

Assessing the Burden of Perioperative Atrial Fibrillation in Patients Undergoing Cardiac Surgery

Brigham and Women's Hospital1 个研究点 分布在 1 个国家目标入组 150 人开始时间: 2021年9月14日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
150
试验地点
1
主要终点
Atrial Fibrillation

研究概览

简要总结

Background and Significance:

In the United States approximately 220,000 patients undergo cardiac surgery per annum. Among potential complications, the incidence of atrial fibrillation (AF) is estimated at 30 - 60 %, and therefore presents the most common adverse event after cardiac surgery. Multiple complications may be associated with AF: Patients are usually subject to an increased length-of-stay in the intensive care unit and in the hospital. Furthermore, the risk for stroke and development of long-term AF is elevated, while further anticoagulation is required putting the patient at risk for bleeding. On average, an additional $10,000 - $20,000 is spent for each patient with AF. However, the exact burden of postoperative AF still remains unknown.

Specific Aims of Research Project:

  1. To collect data from an electrocardiogram (EKG) monitoring patch, we aim to accurately determine the prevalence of atrial fibrillation in patients undergoing cardiac surgery at our center.
  2. To collect data on epidemiological characteristics to investigate risk factors for developing perioperative atrial fibrillation in patients undergoing cardiac surgery. This will allow us to create robust risk prediction models.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
20 Years 至 90 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Elective open heart surgery
  • Age > 20 years

排除标准

  • Refusal to participate (patient or health care proxy)
  • Participation in other pharmacological trials
  • Lack of data or poor data quality which cannot be analyzed for any heart rhythm in 80% of the postoperative study period.

结局指标

主要结局

Atrial Fibrillation

时间窗: Up to 30 days after discharge from the hospital

Atrial Fibrillation

次要结局

  • Other arrhythmias(Up to 30 days after discharge from the hospital)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Jakob Wollborn, MD

Assistant Professor

Brigham and Women's Hospital

研究点 (1)

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