Assessing the Burden of Perioperative Atrial Fibrillation in Patients Undergoing Cardiac Surgery
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- Atrial Fibrillation
研究概览
简要总结
Background and Significance:
In the United States approximately 220,000 patients undergo cardiac surgery per annum. Among potential complications, the incidence of atrial fibrillation (AF) is estimated at 30 - 60 %, and therefore presents the most common adverse event after cardiac surgery. Multiple complications may be associated with AF: Patients are usually subject to an increased length-of-stay in the intensive care unit and in the hospital. Furthermore, the risk for stroke and development of long-term AF is elevated, while further anticoagulation is required putting the patient at risk for bleeding. On average, an additional $10,000 - $20,000 is spent for each patient with AF. However, the exact burden of postoperative AF still remains unknown.
Specific Aims of Research Project:
- To collect data from an electrocardiogram (EKG) monitoring patch, we aim to accurately determine the prevalence of atrial fibrillation in patients undergoing cardiac surgery at our center.
- To collect data on epidemiological characteristics to investigate risk factors for developing perioperative atrial fibrillation in patients undergoing cardiac surgery. This will allow us to create robust risk prediction models.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 90 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Elective open heart surgery
- •Age > 20 years
排除标准
- •Refusal to participate (patient or health care proxy)
- •Participation in other pharmacological trials
- •Lack of data or poor data quality which cannot be analyzed for any heart rhythm in 80% of the postoperative study period.
结局指标
主要结局
Atrial Fibrillation
时间窗: Up to 30 days after discharge from the hospital
Atrial Fibrillation
次要结局
- Other arrhythmias(Up to 30 days after discharge from the hospital)
研究者
Jakob Wollborn, MD
Assistant Professor
Brigham and Women's Hospital
