Comparison of accuracy among near-infrared oxygenation monitors using ischemia and reperfusion of upper extremities

Not Applicable

• Conditions: Ischemic diseases in upper extremities

• Registration Number: JPRN-UMIN000026435
• Lead Sponsor: Aichi Medical University, School of Medicine

Brief Summary

The tissue oxygenation index (TOI), regional saturation of oxygen (rSO2), skin tissue oxygenation (StO2), and FBF values were evaluated in the forearm. Medial rSO2 values at 1 to 3 minutes after the termination of brief ischemia were higher than lateral rSO2 and respective TOI values. FBF and StO2 values quickly increased according to the cessation of brief ischemia, whereas the medial and lateral values did not differ during and after the brief ischemia. TOI and StO2, but not rSO2, reflected changes in FBF of both medial and lateral sides simultaneously in response to the reperfusion after brief ischemia. The muscle tissue oxygenation during reperfusion favors the use of TOI and StO2, but not rSO2, as the surrogate parameter.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-03-07
• Study Completion: 2017-07-31
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Not provided

Exclusion Criteria

Subjects with the history of redness or rash on their forearm were excluded from this study.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
How different tissue oxygenation parameters derived from NIRS reflect the changes in the forearm blood flow according to the brief ischemia and the subsequent reperfusion.

Secondary Outcome Measures

Name	Time	Method
Whether values of these parameters move in parallel with the medial and lateral sides of forearm blood flow.