Assessment of the Efficacy of Microosteoperforations Versus Injectable Platelet-rich Fibrin During Orthodontic Leveling and Alignment of Mandibular Incisors: A Comparative Clinical Trial

Al-Azhar University1 site in 1 country24 target enrollmentAugust 1, 2024

ConditionsEffect of Platelet Rich Fibrin Versus Microosteoperforation Compaed to Control Group Toothmovement

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Effect of Platelet Rich Fibrin Versus Microosteoperforation Compaed to Control Group Toothmovement
Sponsor: Al-Azhar University
Enrollment: 24
Locations: 1
Primary Endpoint: assessment of acceleration of leveling and alignment of mandibular incisors
Status: Enrolling By Invitation
Last Updated: last year

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The aim of this prospective clinical study will be to compare the efficacy of micro osteoperforations versus injectable platelet-rich fibrin during orthodontic leveling and alignment of mandibular incisors.

Registry

clinicaltrials.gov

Start Date

August 1, 2024

End Date

December 1, 2024

Last Updated

last year

Study Type

Interventional

Study Design

Factorial

Sex

All

Investigators

Sponsor

Al-Azhar University

Responsible Party

Principal Investigator

farouk ahmed hussein

principal investigator

Al-Azhar University

Eligibility Criteria

Inclusion Criteria

•An age range from 15 to 25 years.
•Participants who had a full set of permanent dentitions excluding the third molar.
•Participants who had moderate crowding in the mandibular arch according to Little's irregularity index that necessitates non-extraction treatment in the mandibular arch.
•Normal vertical facial proportions.
•Participants who had good oral hygiene and no periodontal disease.
•No systemic diseases or regular medication that could interfere and/or affect orthodontic teeth movement.
•No evidence of craniofacial anomalies, such as clef lip and palate or previous history of trauma, bruxism, or parafunction.
•No tooth size, shape, or root abnormalities visible on patient's radiographic records.

Exclusion Criteria

•Previous orthodontic treatment.
•Any skeletal dysplasia or craniofacial malformation.
•Retained primary or missing permanent teeth in the anterior area, and any kind of tooth/root shape anomaly or history of trauma affecting the incisors.
•Systemic diseases or regular use of medications that could interfere with OTM.
•Patients with root resorption, impacted canines, or dental anomalies.
•Poor oral hygiene and uncontrolled periodontal diseases.