Registration of a aqueous humor-cytokine and -protein profile in glaucoma

• Conditions: H40.1; H40.8; Primary open-angle glaucoma; Other glaucoma

• Registration Number: DRKS00008120
• Lead Sponsor: niklinik Köln, Zentrum für Augenheilkunde

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2015-05-18
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

1.all types of primary and secondary glaucoma and healthy controls.
2.Requirement for cataract-, glaucoma- or corneal surgery.

Exclusion Criteria

1.No need for ophthalmo-surgery.
2.No signed declaration of consent.

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Aim of the study: <br>Measurement and comparison of intraocular proteins by intraoperative aqueous humor-extraction in patients with primary and secondary open-angle glaucoma and healthy age-matched controls who need ophthalmo-surgery because of other diseases. <br><br>Study schedule:<br>It is planned to recruit 200 probes from the routine patient base at the Department of Ophthalmology, University of Cologne, Germany. The probe-extraction will only be performed if a standard ophthalmo-surgery is necessary. The protein- and cytokine-profiles will be analysed by mass spectrometry, antibody array analysis, multiplex microbead assay and ELISA. <br>