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Clinical Trials/NCT01606670
NCT01606670
Completed
Not Applicable

A Multicenter, Non-interventional Study With Neupro® to Evaluate the Perception of Pain Associated With Idiopathic Parkinson's Disease

UCB Pharma GmbH27 sites in 2 countries93 target enrollmentMay 2012

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Idiopathic Parkinson's Disease
Sponsor
UCB Pharma GmbH
Enrollment
93
Locations
27
Primary Endpoint
Change From Baseline to Visit 2 in the Sum Score Calculated From the 4 Items of the Affective Dimension of the Pain Description List (Schmerzbeschreibungsliste SBL, Question 10) of the German Pain Questionnaire
Status
Completed
Last Updated
8 years ago

Overview

Brief Summary

The primary objective of this study is to evaluate the perception of pain associated with Parkinson´s Disease in patients who receive Neupro® for the first time.

Registry
clinicaltrials.gov
Start Date
May 2012
End Date
July 2014
Last Updated
8 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • The decision by the treating physician to treat a patient with Neupro® for the first time is made before the patient's participation in this Non-Interventional Study (NIS)
  • A Patient Data Consent form is signed and dated by the patient
  • Male and female patients that suffer from pain associated with idiopathic Parkinson's Disease according to the physician's assessment
  • Patients have not been treated with Rotigotine in the past

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Change From Baseline to Visit 2 in the Sum Score Calculated From the 4 Items of the Affective Dimension of the Pain Description List (Schmerzbeschreibungsliste SBL, Question 10) of the German Pain Questionnaire

Time Frame: From Baseline (Day 0) to Visit 2 (after at least 4 weeks on a maintenance dose of Neupro®)

The Pain Description List (SBL, question 10) is part of the validated German Pain Questionnaire (DSF). The SBL consists of a 12 item list of adjectives. Each adjective is ranked from 0 (not applicable) to 3 (exactly applicable). 8 of the 12 adjectives will be used to assess the sensory items of pain and 4 adjectives to describe the affective items of pain. The 8 sensory items are used to assess qualitative description of pain. For the 4 affective pain items, a sum score ranges from 0 (not applicable) to 12 (exactly applicable). Values above 8 can be considered noticeable.

Secondary Outcomes

  • Change From Baseline to Visit 2 in the Sum Score of the Unified Parkinson's Disease Rating Scale (UPDRS) Parts II+III(From Baseline (Day 0) to Visit 2 (after at least 4 weeks on a maintenance dose of Neupro®))
  • Change From Baseline to Visit 2 in the Sum Score of the Unified Parkinson's Disease Rating Scale (UPDRS) Part II(From Baseline (Day 0) to Visit 2 (after at least 4 weeks on a maintenance dose of Neupro®))
  • Change From Baseline to Visit 2 in the Short-form Parkinson's Disease Questionnaire (PDQ-8) Total Score(From Baseline (Day 0) to Visit 2 (after at least 4 weeks on a maintenance dose of Neupro®))
  • Change From Baseline to Visit 2 in the Sum Score of the Unified Parkinson's Disease Rating Scale (UPDRS) Part III(From Baseline (Day 0) to Visit 2 (after at least 4 weeks on a maintenance dose of Neupro®))

Study Sites (27)

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