MedPath

Effectiveness of Multisystemic Therapy for Adolescents From Families With Intellectual Disabilities

Recruiting
Conditions
Behavioural Problems
Interventions
Behavioral: Multisystemic therapy - intellectual disabilities
Behavioral: Multisystemic therapy
Registration Number
NCT06032455
Lead Sponsor
De Viersprong
Brief Summary

The goal of this observational study is to determine the effectiveness of a specialisation of multisystemic therapy (MST) for adolescents with severe behavioural problems from families with an intellectual disability (ID; MST-ID).

To achieve this goal, a mixed method study design is used. To this end, a quantitative and a qualitatively primary research question are formulated:

* Is MST-ID superior, when compared to standard MST, in reducing rule-breaking behaviour of adolescents (quantitative)?

* What are the experiences of adolescents and/or parents receiving MST-ID treatment (qualitative)?

Participants will be asked to complete two screeners (questionnaires delivered as a verbal interview) with a total duration of approximately 30 minutes. Other data will be collected through Routine Outcome Monitoring questionnaires that are part of standard MST procedures. To this end, five 'time points' have been identified: T0 (start of MST\[-ID\] treatment), T1 (end of MST\[-ID\] treatment), T2 (follow-up 6 month after MST\[-ID\] treatment), T3 (follow-up 12 month after MST\[-ID\] treatment), and T4 (follow-up 18 month after MST\[-ID\] treatment). The qualitative method used to gain insight into families' experiences is determined in consultation with the families.

To assess the effectiveness of MST-ID, its treatment outcomes will be compared to standard MST treatment outcomes of families with ID.

Detailed Description

Background of the study:

Over the years, a large body of research has shown that adolescents with intellectual disability are 3-4 times more likely to develop severe behaviour problems than adolescents without intellectual disability. Families in which adolescents and/or one or both parent(s) have an intellectual disability (from now on, families with ID) often deal with complex problems, putting the adolescent at an increased risk of out-of-home placement. Multisystemic therapy (MST) is an intensive home-based treatment, effective in reducing severe behaviour problems and preventing the out-of-home placement of adolescents. A specialisation of MST has been developed for families with ID: MST-ID. In MST-ID, among other alterations, simplified language and visual support is used, sessions are more structured and more time is scheduled for practicing exercises, and extra attention is paid to the generalisation of what has been learned in the sessions (with the aim of attaining long-term outcomes). Pilot studies show that when compared to standard MST, MST-ID shows similar or better treatment outcomes in families with adolescents with ID. Meanwhile, MST-ID has been disseminated more widely and the target population extended by including families in which only the parent(s) have an ID.

Objective of the study:

The aim of this study is to investigate the effectiveness of MST-ID for adolescents with severe behavioural problems from families with an intellectual disability (ID), compared to standard MST. It is hypothesised that MST-ID is more effective - in terms of fewer behavioural problems, more adolescents living at home, being in school/work, no new police contacts, less parenting stress - than standard MST. Treatment outcomes are considered both quantitatively and qualitatively.

Study design:

Quantitatively, the Propensity Score (PS) method is used to balance treatment groups and, combined with Multilevel Modelling (MLM), to estimate treatment effect over time. Qualitatively, the experiences of approximately 10 adolescents and/or parents are centralised. The qualitative research methods will be decided upon in a participatory manner with respondents (examples of potential research methods are interviews, focus group discussions, or photo elicitation).

Study population:

Adolescents (10-19y) with severe behavioural problems or delinquent behaviours, and their parent(s) receiving MST(-ID) treatment. All research participants must be from families where either the adolescent and/or parent(s) has/have ID.

Intervention:

Following standard referral procedures, families were either referred to standard MST or MST-ID treatment (i.e., non-randomly). Both standard MST and MST-ID are intensive, home-based treatments with 3-5 home visits per week, targeting the severe behavioural problems of adolescents across multiple life domains. MST-ID is tailored to the needs and skill deficits of adolescents and/or parents with ID. Concretely, more attention is paid to how therapists create engagement, implement interventions, and realise support from informal supports, in a tailored, developmentally appropriate, and simplified manner (meaning in a more structured way and using accessible language, among others), when compared to standard MST.

Research questions:

Building on the objectives, the following research questions were formulated:

Primary research questions:

1. Is MST-ID superior, when compared to standard MST, in reducing rule-breaking behaviour of adolescents, according to parents?

2. Is MST-ID superior, when compared to standard MST, in reducing rule-breaking behaviour of adolescents, according to adolescents?

Secondary research questions:

3. Is MST-ID superior, when compared to standard MST, in reducing externalising and internalising behavioural problems of adolescents, according to parents?

4. Is MST-ID superior, when compared to standard MST, in reducing externalising and internalising behavioural problems of adolescents, according to adolescents?

5. Is MST-ID superior, when compared to standard MST, in reducing parenting stress?

6. Is MST-ID superior, when compared to standard MST, in preventing short and long term out-of-home placement, delinquency, truancy or joblessness, and addictions of adolescents?

7. Is MST-ID superior, when compared to standard MST, in realising improvements on family's social networks?

8. Is MST-ID superior, when compared to standard MST, in improving the instrumental outcome parenting skills?

9. Is MST-ID superior, when compared to standard MST, in improving the instrumental outcome family relations?

10. Is MST-ID superior, when compared to standard MST, in improving the instrumental outcome social support?

11. Is MST-ID superior, when compared to standard MST, in improving the instrumental outcome adolescent success in an educational or vocational setting?

12. Is MST-ID superior, when compared to standard MST, in improving the instrumental outcome adolescent involvement with pro-social peers?

13. Is MST-ID superior, when compared to standard MST, in improving the instrumental outcome change in adolescent problem behaviour?

14. What are the experiences of adolescents and/or parents receiving MST-ID treatment?

15. Do effects across subgroups of adolescents and/or parents with ID differ?

MST-ID is expected to be superior in achieving the aforementioned outcomes (#1-13) when compared to standard MST. Research questions #14-15 will be assessed exploratively, therefore no hypotheses have been formulated.

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
470
Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Families receiving MST-IDMultisystemic therapy - intellectual disabilitiesFamilies in which the adolescent and/or parent(s) has/have an ID receiving MST-ID treatment
Families receiving standard MSTMultisystemic therapyFamilies in which the adolescent and/or parent(s) has/have an ID receiving standard MST treatment
Primary Outcome Measures
NameTimeMethod
Rule-breaking behaviour of adolescents - parentsStart of MST(-ID) treatment (T0) until 18-month follow up (T4)

Rule-breaking behaviour of adolescents according to parents will be assessed using the Child Behavior Check List (CBCL). The CBCL consists of 118 questions rated on a 3-point scale from 0 (absent) to 2 (occurs often). Higher scores indicate that adolescents experience more problems.

Rule-breaking behaviour of adolescents - adolescentsStart (T0) and end (T1) of MST(-ID) treatment, an average of 4 months in between

Rule-breaking behaviour of adolescents according to parents will be assessed using the Youth Self Report (YSR). The YSR consists of 112 questions rated on a 3-point scale from 0 (absent) to 2 (occurs often). Higher scores indicate that adolescents experience more problems.

Secondary Outcome Measures
NameTimeMethod
Externalising and internalising behavioural problems of adolescents - parentsStart of MST(-ID) treatment (T0) until 18-month follow up (T4)

Externalising and internalising behavioural problems of adolescents will be assessed using the Child Behavior Check List (CBCL). The CBCL consists of 118 questions rated on a 3-point scale from 0 (absent) to 2 (occurs often). Higher scores indicate that adolescents experience more problems.

Externalising and internalising behavioural problems of adolescents - adolescentsStart (T0) and end (T1) of MST(-ID) treatment, an average of 4 months in between

Externalising and internalising behavioural problems of adolescents according to adolescents will be assessed using the Youth Self Report (YSR). The YSR consists of 112 questions rated on a 3-point scale from 0 (absent) to 2 (occurs often). Higher scores indicate that adolescents experience more problems.

DelinquencyStart of MST(-ID) treatment (T0) until 18-month follow up (T4)

Delinquency of adolescents is operationalized as police contact and will be assessed using the SDI 3.0.

IO Percentage of families with change in adolescent problem behaviourEnd of MST(-ID) treatment, an average of 4 months after start of treatment

MST's so called "instrumental outcomes" (IOs) identify skills which are instrumental to achieving positive treatment outcomes and are reported by therapists. The sixth IO assesses whether or not the adolescent obtained changes in problem behaviour that were sustained for 3-4 weeks, answered 'yes' or 'no'.

School going or workStart of MST(-ID) treatment (T0) until 18-month follow up (T4)

The adolescent's school going or work is operationalised as "school going that meets the expectations of the school or public education law officer or work that meets the expectations of caregivers and the referring agent" and will be assessed using the SDI 3.0.

AddictionsStart of MST(-ID) treatment (T0) until 18-month follow up (T4)

Addictions of adolescents are operationalised as "adolescent drug misuse/abuse, screen or game dependency that has resulted in addiction, and/or other addictions" and will be assessed using the SDI 3.0.

IO Percentage of families with improved social supportEnd of MST(-ID) treatment, an average of 4 months after start of treatment

MST's so called "instrumental outcomes" (IOs) identify skills which are instrumental to achieving positive treatment outcomes and are reported by therapists. The third IO assesses whether or not families show improved social support, answered 'yes' or 'no'.

Parenting stressStart of MST(-ID) treatment (T0) until 18-month follow up (T4)

Parenting stress will be assessed using the Parenting Stress Questionnaire (PSQ). The PSQ consists of 34 questions rated on a 4-point scale from 1 (not true) to 4 (very true). Higher scores indicate more parenting stress.

Out-of-home placementStart of MST(-ID) treatment (T0) until 18-month follow up (T4)

Out-of-home placement of adolescents will be assessed using the Social Demographic Information 3.0 questionnaire (SDI 3.0).

IO Percentage of families with improved parenting skillsEnd of MST(-ID) treatment, an average of 4 months after start of treatment

MST's so called "instrumental outcomes" (IOs) identify skills which are instrumental to achieving positive treatment outcomes and are reported by therapists. The first IO assesses whether or not families show improved parenting skills, answered 'yes' or 'no'.

IO Percentage of families with improved family relationsEnd of MST(-ID) treatment, an average of 4 months after start of treatment

MST's so called "instrumental outcomes" (IOs) identify skills which are instrumental to achieving positive treatment outcomes and are reported by therapists. The second IO assesses whether or not families show improved family relations, answered 'yes' or 'no'.

Social networkStart of MST(-ID) treatment (T0) until 18-month follow up (T4)

Social network is operationalised as "forms of social network available to a family and number of supports (read: individuals) that are available to the family" and will be assessed using the SDI 3.0.

IO Percentage of families with adolescent success in an educational or vocational settingEnd of MST(-ID) treatment, an average of 4 months after start of treatment

MST's so called "instrumental outcomes" (IOs) identify skills which are instrumental to achieving positive treatment outcomes and are reported by therapists. The fourth IO assesses whether or not the adolescent obtained success in an educational or vocational setting, answered 'yes' or 'no'.

IO Percentage of families with adolescent involvement with pro-social peersEnd of MST(-ID) treatment, an average of 4 months after start of treatment

MST's so called "instrumental outcomes" (IOs) identify skills which are instrumental to achieving positive treatment outcomes and are reported by therapists. The fifth IO assesses whether or not the adolescent is involved with pro-social peers, answered 'yes' or 'no'.

Trial Locations

Locations (4)

Pactum

🇳🇱

Zetten, Netherlands

De Viersprong

🇳🇱

Halsteren, Netherlands

Stichting Prisma

🇳🇱

Waalwijk, Netherlands

Koraal

🇳🇱

Sittard, Netherlands

© Copyright 2025. All Rights Reserved by MedPath