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Hypertension Treatment Adherence Improving Trial

Not Applicable
Conditions
Hypertension,Essential
Interventions
Other: Usual care
Other: Educational program for hypertensive patients
Registration Number
NCT04565548
Lead Sponsor
The Hong Kong Polytechnic University
Brief Summary

Persistent adherence to lifestyle modifications and blood pressure lowering medications were the best way to control blood pressure. But low adherence was noted in reviews and studies resulting those taking blood pressure lowering medications could not achieve a controlled blood pressure. In this study, a theory-guided educational program will be developed with an aim to improve the blood pressure, self-efficacy and adherence behaviors among those diagnosed with high blood pressure in the community. 148 participants will be recruited and divided into control group and intervention group randomly in a ratio of 1:1. The intervention group will receive the theory-guided educational program, while the control group will receive the usual care. The study will last for 12 weeks. Data will be collected at baseline, week 8 and week 12. SPSS and generalized estimating equations model will be employed for data analysis. The results will inform an effective way to conduct health promotion in community. The improved adherence to lifestyle modifications and medications will be beneficial to the clients' health.

Detailed Description

Persistent adherence to lifestyle modifications and anti-hypertensive medications were emphasized in hypertension guidelines to control blood pressure effectively. But low adherence to lifestyle modifications and medication were noted in reviews and studies. Low adherence would lead to those received hypertension treatment did not achieve a controlled blood pressure. In this study, an educational program guided by the Health Promotion Model will be conducted to examine the effect on blood pressure, self-efficacy and treatment adherence among hypertensive patients in the community. A 2-arm parallel randomized control trial will be conducted. 148 participants will be recruited and divided into control and intervention group in a ration of 1:1. The intervention group will receive the theory-guided educational program, while the control group will receive the usual care. The study will last for 12 weeks. Data will be collected at baseline, week 8 and week 12. SPSS and generalized estimating equations model will be employed for data analysis. The results will inform community healthcare professionals about the effective way for health promotion, to enhance the adherence to lifestyle modifications and medications among hypertensive clients resulting sustainable benefits to the clients' health.

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
148
Inclusion Criteria
  • Own a mobile phone and able to use
  • Able to communicate with Cantonese and read Chinese
  • Diagnosed with hypertension and taking at least one anti-hypertensive medication
  • SBP = 131~159 mmHg or DBP = 81~99 mmHg
Exclusion Criteria
  • Renal hypertension
  • Mini-Cog < 3

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
ControlUsual careParticipants will receive the usual care and non-hypertension related text messaging for 12 weeks.
InterventionEducational program for hypertensive patientsParticipants will receive the newly developed theory-guided program for 12 weeks.
Primary Outcome Measures
NameTimeMethod
Change of blood pressure at week 8 and week 12Baseline, week 8, week 12

Systolic and diastolic blood pressure (mmHg) is measured by a trained research assistant. A validated upper-arm blood pressure monitor is used for the blood pressure measurement.

Secondary Outcome Measures
NameTimeMethod
Change of Self-efficacy for managing chronic disease (SEMCD) at week 8 and week 12Baseline, week 8, week 12

SEMCD consists of six self-report items to measure the self-efficacy of hypertension management. Summative scores range from 6 to 60. The scale was translated into Chinese and yielded a good reliability (Cronbach's alpha = 0.88-0.98; teste-retest reliability = 0.73-0.98) in Chinese hypertensive adults and Chinese older adults.

Change of Treatment Adherence Questionnaire for Patients with Hypertension (TAQPH) at week 8 and week 12Baseline, week 8, week 12

TAQPH consists of 28 items and covers the adherence to medications and lifestyle modifications in hypertension management. The responses are made on a 1-4 scale, and the sum of the score ranges from 28 to 112. The TAQPH has been proved to be reliable with good Cronbach's alpha coefficient 0.86 for Chinese hypertensive adults.

Trial Locations

Locations (2)

Community Health Centres

🇨🇳

Shenzhen, Shenzhen, China

Complexo de Apoio à Família e de Serviço Comunitário de Seac Pai Van da União Geral das Associações dos Moradores de Macau

🇭🇰

Kowloon, Hong Kong

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