Comparison of Parameters That Can be Used to Predict Frailty in Elderly Femur Fracture Patients.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Correlation between Rectus Femoris Muscle Thickness and Frailty Score
研究概览
简要总结
This study aims to evaluate the frailty status of elderly patients undergoing surgery for hip fractures (femur trochanteric fractures). Since frailty is a critical factor in surgical outcomes and recovery, researchers want to find simple, fast, and objective ways to measure it. This study will investigate muscle thickness measured by ultrasound, handgrip strength measured by a dynamometer, and routine blood test values can accurately predict a patient's frailty level. If these objective methods are proven effective, it will help anesthesia and surgical teams manage the perioperative process more safely for high-risk elderly patients
详细描述
65 and over years old elderly patients admitted to the orthopedics department with a diagnosis of trochanteric femur fracture will be enrolled in this study.
Preoperative Assessment: A researcher anesthesiologist, who is not involved in the patient's perioperative clinical management, will conduct the assessments to ensure objectivity. One day prior to the scheduled surgery, the following procedures will be performed:
Frailty Evaluation: Clinical frailty status will be determined using the Clinical Frailty Scale. In conjunction with this, handgrip strength will be measured using a calibrated hand dynamometer.
Ultrasonographic Measurements: Ultrasound will be used to measure the thickness of the rectus femoris muscle and the distance from the femur to the skin. These measurements will serve as objective indicators of musculoskeletal status.
Data Collection: Demographic data (age, weight, height, comorbidities) and routine preoperative laboratory results will be recorded from the hospital's electronic medical records. Laboratory parameters to be analyzed include:
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients aged 65 years and older.
- •Confirmed diagnosis of trochanteric femur fracture.
- •Planned for orthopedic surgery under general or regional anesthesia.
- •Ability to provide written informed consent (either by the patient or a legal representative).
排除标准
- •Patients with advanced dementia or severe cognitive impairment who cannot cooperate with the handgrip strength test or Fried criteria questionnaire.
- •Patients with terminal-stage diseases or those under palliative care.
- •History of neuromuscular diseases or severe muscle-wasting conditions that affect the lower limbs (e.g., advanced muscular dystrophy).
- •Patients with active infections or skin lesions at the site of ultrasound measurement (rectus femoris area).
- •Emergency cases requiring immediate surgery where preoperative assessment cannot be completed.
研究组 & 干预措施
Elderly Hip Fracture Patients
Patients aged 65 and older who have been diagnosed with a trochanteric femur fracture and are scheduled for orthopedic surgery.
干预措施: Clinical and Functional Assessment (Other)
Elderly Hip Fracture Patients
Patients aged 65 and older who have been diagnosed with a trochanteric femur fracture and are scheduled for orthopedic surgery.
干预措施: Rectus femoris thickness measurement (Other)
结局指标
主要结局
Correlation between Rectus Femoris Muscle Thickness and Frailty Score
时间窗: Preoperative (within 24 hours before surgery)
Evaluation of the relationship between clinical frailty status (measured by the Clinical Frailty Scale) and objective muscle mass (measured as rectus femoris thickness in millimeters via ultrasonography). Over 5 point indicate frailty.
次要结局
- Predictive Value of Handgrip Strength for Frailty(Preoperative)
- Correlation of Laboratory Biomarkers with Frailty Status(1 day before operation)
- Hematological Indicators of Frailty(1 day before operation)
研究者
ali ihsan uysal
Ass.Prof.
Muğla Sıtkı Koçman University