Serratus-intercostal Plane Block Versus Quadratus Lumborum Block in Nephrectomy: Randomized Study

Completed

• Conditions: Kidney Injury
• Interventions: Device: ultrasound device; Drug: Levobupivacaine

• Registration Number: NCT04431388
• Lead Sponsor: Hospital Medina del Campo

Brief Summary

Performing the nephrectomy by laparoscopy has decrease the incidence of postoperative pain, but there are still some patients who describe a severe pain after this surgery. Regional techniques allow a better recovery quality and adequate- managed pain control.

Detailed Description

Adequate control of pain in patients with nephrectomy is a challenge for the anesthesiologist who must achieve an early recovery with minimal adverse effects. Within a multimodal strategy, the work hypothesis is based on comparing the analgesic efficacy of two regional techniques in patients undergoing nephrectomy, in terms of quality of postoperative recovery, pain control, absence of adverse effects and ease of performance.

Study Timeline

• Study First Submitted: 2020-06-10
• Study First Submitted QC: 2020-06-12
• Study First Posted: 2020-06-16
• Study Start: 2021-06-01
• Primary Completion: 2023-06-01
• Study Completion: 2023-12-01
• Status Verified: 2024-03
• Last Update Submitted: 2024-03-05
• Last Update Posted: 2024-03-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 126

Inclusion Criteria

• signature of informed consent
• age > 18 years
• ASA risk scale < IV
• Scheduled to nephrectomy.

Exclusion Criteria

• Patients with cognitive impairment or inability to sign informed consent,
• Refused to participate
• Hypersensitivity to the drugs used
• contraindication of regional technique (coagulopathy, infection)
• history of chronic pain.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
SIPB (block)	ultrasound device	Patients undergone nephectomy and who received SIPB as analgesia
QL block	ultrasound device	Patients undergone nephectomy and who received QL as analgesia
SIPB (block)	Levobupivacaine	Patients undergone nephectomy and who received SIPB as analgesia
QL block	Levobupivacaine	Patients undergone nephectomy and who received QL as analgesia

Primary Outcome Measures

Name	Time	Method
pain control and quality life.Numeric rating scale (NRS)	"24 postoperative hours"	To assess whether SIPB is superior in pain control
QoR15	"24hours"	Postoperative quality recovery

Secondary Outcome Measures

Name	Time	Method
Side effects	"24hours"	We assessed the side effects of opioids
Opioids consumption	"48 hours"	Second outcomes was to know the consumption of intaoperative fentanyl and postoperative morphine and their side effects

Trial Locations

Locations (1)

María Teresa Fernandez; 🇪🇸 Valladolid, VA, Spain