Comparison of the effectiveness of GnRH agonist stop-Antagonist protocol versus GnRH antagonist protocol in IVF candidate patients
- Conditions
- Infertility.Female infertility
- Registration Number
- IRCT20110731007165N10
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 74
The criteria for diagnosing poor ovarian response are two of the following:1- Age 40 or older 2 - History of poor ovarian response (POR) in the previous cycle (oocyte less than 3 in a conventional protocol), 3-Antral follicle count (AFC) less than 5-7 or Anti-Müllerian hormone (AMH) <0.5-1.1.
Twice poor ovarian response after maximal ovarian stimulation is sufficient reason to introduce the individual as POR without the need for other criteria.
Polycystic ovarian syndrome
Hypothalamic amenorrhea
Uterine congenital anomalies and uterine cavity abnormalities (Bicorn uterus, Unicorn uterus, Asherman, Liomyuma, Polyp, etc.)
Repeated IVF failure (more than three consecutive failures)
Endocrine disorders (diabetes, thyroid disease, antipolipid syndrome, cardiovascular and liver disease),
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method umber of mature oocytes. Timepoint: During IVF process. Method of measurement: Embryologist opinion.;Number of mature oocytes at retrieval. Timepoint: During IVF process. Method of measurement: Embryologist opinion.
- Secondary Outcome Measures
Name Time Method Embryo quality. Timepoint: Embryo formation. Method of measurement: By the embryologist.;Oocyte count. Timepoint: Puncture Day. Method of measurement: by embryologist.