A clinical trial to evaluate the effects of two drugs, dexmedetomidine and lignocaine, on stress and pain in patients undergoing head surgeries
Not Applicable
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2022/07/044048
- Lead Sponsor
- AIIMS Rishikesh
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1]ASA grade I-II patients
2]Age 18-60
3]GCS score 13-15
4]Patients scheduled for elective supratentorial
craniotomy
Exclusion Criteria
1]Refusal of consent
2]Known or suspected allergy to study drug
3]Deranged liver function test and coagulation
disorder
4]Poor cognitive function preoperatively
5]Uncontrolled hypertension, diabetes or heart
disease
6]Psychotic disorders or substance abuse
7]Chronic headache or on analgesics for long
duration
8]2nd and 3rd degree heart block
9]Patients using beta blockers
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.Intraoperative hemodynamic variations <br/ ><br>2.Response to noxious stimulus of surgery <br/ ><br>3.Postoperative pain as evaluated by CPOT <br/ ><br>Timepoint: 1. Intraoperative <br/ ><br>2.postoperative
- Secondary Outcome Measures
Name Time Method 1.Brain relaxation score <br/ ><br>2.Incidence of postoperative cognitive dysfunction <br/ ><br>3.Quality of recovery scores <br/ ><br>4.Effects on extubation criteria <br/ ><br>Timepoint: 1. intraoperative <br/ ><br>2. postoperative