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Effect of Ginseng on Blood Pressure

Completed
Conditions
Blood Pressure
Registration Number
NCT01913210
Lead Sponsor
Unity Health Toronto
Brief Summary

To determine the effect of ginseng on blood pressure control.

Detailed Description

The effect of ginseng on blood pressure control is controversial, originating from an early 1970s observational study, suggesting that ginseng may adversely effect blood pressure. Despite these early findings, extensive research has since suggested that ginseng may have a positive effect on blood pressure. The current study will help clarify present uncertainty on the effect of ginseng on blood pressure control.

This systematic review and meta-analysis will follow The Cochrane Handbook for Systematic Reviews of Interventions. MEDLINE, EMBASE, CINAHL and The Cochrane Central Register of Controlled Trials will be searched using appropriate search terms. Intervention trials that investigate the effect of ginseng on blood pressure in humans will be included.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
500
Inclusion Criteria
  • clinical trials in humans
  • randomized treatment allocation
  • ≥ 1 month
  • suitable control
  • viable endpoint data
Exclusion Criteria
  • non-human studies
  • non-randomized treatment allocation
  • < 1 month
  • lack of a suitable control
  • no viable endpoint data
  • trials where ginseng is part of a multi-herbal treatment

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Systolic Blood Pressure1 month
Secondary Outcome Measures
NameTimeMethod
Mean Arterial Pressure1 month
Diastolic Blood Pressure1 month

Trial Locations

Locations (1)

The Toronto 3D Knowledge Synthesis and Clinical Trials Unit, Clinical Nutrition and Risk Factor Modification Centre

🇨🇦

Toronto, Ontario, Canada

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