Is beta-lactam therapy, until the patient has been afebrile for 48 hours (at least 5 days), sufficient for the treatment of community-acquired pneumonia?
Completed
- Conditions
- Community-acquired pneumoniaRespiratoryPneumonia
- Registration Number
- ISRCTN14523624
- Lead Sponsor
- The Research Committee of Orebro County Council (Sweden)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 200
Inclusion Criteria
Adult patients with uncomplicated febrile community-acquired pneumonia, with chest X-ray infiltrates, who initially experience improvement with beta-lactam monotherapy
Exclusion Criteria
Nursing home resident, hospitalisation during the preceding month, antibiotic treatment for any reason during the preceding week, ongoing antipyretic medication. Inability to make a telephone conversation or to attend to a follow-up visit
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Clinical cure at the four-week-visit<br>2. Recurrence of pneumonia within one month
- Secondary Outcome Measures
Name Time Method 1. Resolution of X-ray infiltrates<br>2. C-reactive protein-level at the four-week-visit<br>3. Reported fever, cough and of physical and mental condition at the telephone conversation or at the follow-up visit