The role of long chain omega-3 polyunsaturated fatty acids (fish oil) on weight management

Not Applicable

Completed

• Conditions: obesity; Diet and Nutrition - Obesity

• Registration Number: ACTRN12610000659000
• Lead Sponsor: The University of Newcastle

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2010-08-12
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Body Mass Index (BMI) between 30 and 40. Can consume fish. Can swallow capsules

Exclusion Criteria

BMI >40; Diabetic; Already consuming fish oil capsules or 2 or more oily fish meals/week; Has an inflammatory condition

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Comparison of % change in total body fat from baseline between groups using bioelectrical impedance.[At baseline, at 12 weeks, at 22 weeks];Comparison of % change in fat free mass from baseline between groups using bioelectrical impedance assessment[At baseline, at 12 weeks, at 22 weeks];Comparison of % change in weight from baseline between groups using a calibrated balance beam scale to measure weight[At baseline, at 12 weeks, at 22 weeks]

Secondary Outcome Measures

Name	Time	Method
Comparison of changes in inflammatory biomarkers from baseline between groups using commerically available Enzyme Linked ImmunoSorbent Assays (ELISAs), namely Leptin, Adiponectin, Interleukin-6 (IL-6), Tumour Necrosis Factor alpha (TNFa) and Leukotriene B4 (LTB4). Also C-Reactive Protein which will be analysed by Hunter Area Pathology Services.[At baseline, at 12 weeks, at 22 weeks];Comparison of changes in blood glucose and blood lipids from baseline between groups. Fasting blood glucose and blood lipids will be analysed by Hunter Area Pathology Services.[At baseline, at 12 weeks, at 22 weeks];Comparison of changes in plasma fatty acids between groups. Plasma fatty acid profiles will be determined using Gas Chromatography analysis.[At baseline, at 12 weeks, at 22 weeks]