Extended rhythm SCreening for AtRial Fibrillation in cryptogenic stroke patients
Completed
- Conditions
- stroke cerebrovascular accident1000752110007963
- Registration Number
- NL-OMON41263
- Lead Sponsor
- Medisch Spectrum Twente
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 50
Inclusion Criteria
Patients > 18 years of age
Recent episode (<=60 days) of cryptogenic ischemic stroke
Undetermined etiology with negative evaluation (including cardioembolism work-up) according to the TOAST criteria
Implantation of an implantable loop recorder within two months after index event
Able of providing informed consent
Exclusion Criteria
Pre-existing indication for vitamin K antagonist
Untreated hyperthyroidism
Indication for pacemaker implantation, ICD or CRT device
Severe co-morbidity not likely to complete follow-up for one year
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The percentage of patients with documented AF based on implantable cardiac<br /><br>monitor registration during a follow-up period of at least 12 months after an<br /><br>episode of cryptogenic stroke. Compared to usual care consisting of an 12 lead<br /><br>ECG upon outpatient clinic visit. An episode of AF is defined as an episode of<br /><br>at least 120 seconds duration.</p><br>
- Secondary Outcome Measures
Name Time Method <p>Secondary outcomes include time to first documented AF, incidence of recurrent<br /><br>stroke or TIA and change of oral anticoagulation regimen. Progression of the<br /><br>length and incidence of atrial fibrillation episodes. </p><br>