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Clinical Trials/NCT06631573
NCT06631573
Active, Not Recruiting
N/A

Prosthetic Complications in Fixed All-On-Four Prosthesis Reinforced with Poly Ether Ether Ketone (PEEK) Versus Cobalt Chromium (Co-Cr) Framework in Completely Edentulous Mandibular Arches. (Randomized Controlled Clinical Trial)

Cairo University1 site in 1 country14 target enrollmentJanuary 18, 2024

Overview

Phase
N/A
Intervention
Not specified
Conditions
Complete Edentulism
Sponsor
Cairo University
Enrollment
14
Locations
1
Primary Endpoint
Prosthetic complications
Status
Active, Not Recruiting
Last Updated
last year

Overview

Brief Summary

Prosthetic complication will be measured for all-on-four fixed prosthesis in the mandibular arch in completely edentulous patients.

Detailed Description

Four implants will be placed in the edentulous mandible following all on four surgical protocol. After 3 months as a healing phase, a definitive prosthesis will be fabricated after ensuring the complete osseointegration of all implants. Provisional restorations will be removed, and final impressions will be taken for each patient using addition silicon impression materials. Framework will be constructed using either Cobalt Chromium (Co-Cr) or Poly Ether Ether Ketone (PEEK) according to the randomization process. Jaw relation and try-in will be done to ensure the correct centric relation. Final prosthesis is then screwed to the abutments and the screw hole channels are closed with composite resin restorations. Occlusal adjustments will be done after the delivery and in the subsequent follow up visit. Prosthetic complications (primary outcome) and biological considerations (secondary outcome) will be measured every 3 months along the follow up period which is one year.

Registry
clinicaltrials.gov
Start Date
January 18, 2024
End Date
March 2025
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Mohannad Alaa Eldin Samy

Assistant lecturer - Prosthodontic department - Cairo University

Cairo University

Eligibility Criteria

Inclusion Criteria

  • Any completely edentulous patient (mandible) with an old satisfactory denture requiring an implant-supported restoration.
  • Patients aged from 50 to 70, able to sign an informed consent will be considered eligible for this trial.
  • Implant sites must allow the placement of four implants.
  • Non- heavy Smokers will be included (smoking up to 10 cigarettes/day)
  • In case of post-extractive sites, they must have been healed for at least 3-month before being treated in the study.
  • Patients with no systemic condition that may interfere with implant placement (e.g., Immunosuppressed or immunocompromised patients, patients under treatment of intravenous amino-bisphosphonates)

Exclusion Criteria

  • Patients with poor oral hygiene and motivation.
  • Pregnancy or nursing.
  • Drug abusers.
  • Psychiatric problems or unrealistic expectations.
  • Patients with infection and or inflammation in the area intended for implant placement.
  • Patients participating in other studies, if the present protocol cannot be properly adhered to.
  • Patients with signs of hyperactive muscles.

Outcomes

Primary Outcomes

Prosthetic complications

Time Frame: one year

record any prosthetic problem that occurs during the follow up period (such as screw loosening, screw fracture, prosthesis fracture, ....etc.)

Secondary Outcomes

  • Biological considerations(one year)

Study Sites (1)

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