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Clinical Trials/NCT01109303
NCT01109303
Completed
Not Applicable

Prospective Randomized Multicentric Trial Comparing a Static Implant and a Dynamic Implant in the Surgical Treatment of Ankle Syndesmosis Rupture

Hopital de l'Enfant-Jesus1 site in 1 country70 target enrollmentOctober 2008

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Ankle Syndesmosis Rupture
Sponsor
Hopital de l'Enfant-Jesus
Enrollment
70
Locations
1
Primary Endpoint
Olerud-Molander score
Status
Completed
Last Updated
13 years ago

Overview

Brief Summary

Ankle fracture is frequent and its number is increasing. In Canada, surgical treatment of these lesions is advised and the options currently used all have in common a rigid fixation of the syndesmosis which results in residual stiffness and a high level of secondary surgery, mostly to remove the implant.

The purpose of the study is to compare the treatment of ankle syndesmotic rupture by a dynamic fixation to a static fixation suggesting that the dynamic fixation method will improve the Olerud-Molander functional score of more than 15 points at the 3 months follow-up.

Registry
clinicaltrials.gov
Start Date
October 2008
End Date
January 2012
Last Updated
13 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Hopital de l'Enfant-Jesus
Responsible Party
Principal Investigator
Principal Investigator

Pelet Stephane

Dr Stephane Pelet MD, PhD Orthopedic surgeon

Hopital de l'Enfant-Jesus

Eligibility Criteria

Inclusion Criteria

  • men or women ≥ 18 years-old;
  • ankle fracture type 44-C (AO classification) with an AP, lateral and mortise X-ray views of the ankle and an AP and lateral X-ray views of the leg;
  • open fractures (Gustilo I-IIIb) or closed;
  • trauma-surgery delay of less than 7 days;
  • consent form signed.

Exclusion Criteria

  • ankle fractures without syndesmotic lesion;
  • fracture associated with neuro-vascular lesions (Gustillo IIIc);
  • pathologic fracture;
  • fracture in a polytraumatized patient;
  • fracture of a bone in the ipsilateral leg;
  • men or women \> 65 years-old;
  • chronic cardiac insufficiency (ejection fraction \< 30%);
  • lower leg chronic venous insufficiency;
  • neuro-arthropathic foot (Charcot, diabetes, etc...);
  • body mass index ≥ 40;

Outcomes

Primary Outcomes

Olerud-Molander score

Time Frame: 3 months after surgery

The Olerud-Molander scoring scale was chosen because it adequately represents the ankle performance following surgery (trauma or elective basis). It comprises nine functional parameters which are concerned with primary complaints, the ability to perform simple tasks and the everyday life activities.

Secondary Outcomes

  • Rate of secondary surgery(within one year following surgery)
  • Radiological loss of reduction(12 months after surgery)
  • Implant failure(one year after surgery)
  • American Orthopaedic Foot and Ankle Society (AOFAS) score of hindfoot(12 weeks after surgery)
  • AOFAS score of hindfoot(12 months after surgery)
  • Return to professional activities(3 months after surgery)
  • Pain on visual analog scale (VAS)(12 weeks after surgery)
  • Pain on VAS(12 months after surgery)
  • Range of motion(12 months after surgery)
  • Muscular trophicity measure of the leg(12 months after surgery)
  • Ankle circumference measure(12 months after surgery)

Study Sites (1)

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