A Randomized phaseII trial of chemoradiotherapy with UFT versus S-1 for low rectal cancer
Phase 2
- Conditions
- rectal cancer,lower tumor margin is below the peritoneal reflection
- Registration Number
- JPRN-UMIN000001704
- Lead Sponsor
- Tokushima university
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up continuing
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Not provided
Exclusion Criteria
1,apparent or previous history of interstitinal pneumonitis or pulmonary fibrosis 2,pleural effusion or ascites requiring treatment 3,multiple malignancies 4,infection,paralysis of intestine or ireus 5,diarrhea(watery stool) 6,uncontrollacle diabetes 7,severe complication(heart failure,renal failure,hepatic insufficiency) 8,brain metastasis or treated brain metastasis 9,preqnant or lacting,capable of preqnancy or intend to get preqnant 10,previus serius medical illness or allergy for drug 11,critical mental disturbance 12,systemically administrered of steroids 13,judged in appropriate for this study by the physycians
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method response rate
- Secondary Outcome Measures
Name Time Method pathological complete response rate pathological response rate adverse event overall survival