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Emergency Department CT Scanning for Appendicitis

Not Applicable
Completed
Conditions
Appendicitis
Interventions
Other: Omnipaque
Registration Number
NCT00734825
Lead Sponsor
WellSpan Health
Brief Summary

The purpose of this study is to compare IV contrast only vs. IV and oral contrast Computed Tomography (CT) for the diagnosis of acute appendicitis in adult patients in our emergency department. A secondary purpose will be to design a specific CT for appendicitis protocol at our institution at the conclusion of this study.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
244
Inclusion Criteria
  • 18 years and older who present to the York Hospital Emergency Department with signs and symptoms suggestive of acute appendicitis, but in whom the diagnosis remains unclear as determined by an attending emergency physician or consulting surgeon and in which a CT scan is needed to further assist in the diagnosis
Exclusion Criteria
  • pregnant patients
  • patients with known IV dye or oral contrast allergy
  • patients in whom acute appendicitis is not the primary diagnosis
  • patients with renal insufficiency that may have significant adverse effect from IV dye

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
1OmnipaqueIV contrast
2OmnipaqueIV contrast and oral contrast
Primary Outcome Measures
NameTimeMethod
sensitivity of IV contrast alone for a computed tomography scan for the diagnosis of appendicitis in the adult Emergency Department patient.immediate reading + blinded reading within 48 hours
Secondary Outcome Measures
NameTimeMethod
If IV contrast alone for CT scan is sensitive for the diagnosis of appendicitis in the adult Emergency department patientimmediate reading and blinded reading within 48 hours
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