Effect of Laser Acupuncture on Adhesive Small Bowel Obstruction

Not Applicable

• Conditions: Adhesive Small Bowel Obstruction

• Registration Number: NCT04318821
• Lead Sponsor: Chang Gung Memorial Hospital

Brief Summary

Adhesive small bowel obstruction (ASBO) is one of the most common complications and is a major cause of admission after intra-abdominal surgery. To date, the ideal management of ASBO remains controversial. The aim of this protocol designed as a double-blind randomized controlled trial is to investigate the efficacy of laser acupuncture (LA) therapy in patients with ASBO.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-03-01
• Study First Submitted: 2020-03-16
• Study First Submitted QC: 2020-03-22
• Study First Posted: 2020-03-24
• Status Verified: 2021-07
• Last Update Submitted: 2022-03-08
• Last Update Posted: 2022-03-10
• Primary Completion: 2023-02-28
• Study Completion: 2023-02-28

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 92

Inclusion Criteria

• Aged 20 to 80 years
• Clinical symptoms and signs of mechanical obstruction

Exclusion Criteria

• Clear non-adhesive etiology of small bowel obstruction (e.g. tumor, hernia)
• Emergency surgical intervention before being admitted to the hospital
• Pregnancy
• Local skin infection on the acupoints, and limb amputees.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Success rate of conservative treatment	2 week	Defined as no need for long term nasogastric tube decompression and operative intervention.

Secondary Outcome Measures

Name	Time	Method
Serum ghrelin	Up to 2 weeks	Serum ghrelin
Serum amylase	Up to 2 weeks	Serum amylase
Serum intestinal fatty acid binding protein (I-FABP)	Up to 2 weeks	Serum intestinal fatty acid binding protein (I-FABP)
Time to oral intake	2 weeks	Defined as participants can try intake due to symptoms improved including nausea, vomiting, distension and pain.
Length of hospital stay	Through study completion, an average of 1 year	Date from admission to discharge
Serum lipase	Up to 2 weeks	Serum lipase
Serum cortisol	Up to 2 weeks	Serum cortisol
Serum motilin	Up to 2 weeks	Serum motilin

Trial Locations

Locations (1)

Kaohsiung Chang Gung Memorial Hospital; 🇨🇳 Kaohsiung, Taiwan