Sero-surveillance for Dengue, Chikungunya and COVID
Not Applicable
- Registration Number
- CTRI/2020/11/029141
- Lead Sponsor
- Shikha Dixit
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Survey will be carried out in individuals above 2 years of age (no upper limit on age) and all individuals currently residing and likely to stay till the end of study (1 year) in the study area will be considered eligible for inclusion.
Exclusion Criteria
Individuals who are unlikely to stay in the study area for the next 1 year
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Primary objectives <br/ ><br>I. Estimate the sero-prevalence of SARS-CoV-2 infection in the general population <br/ ><br>II. Estimate the 4 monthly incidence of SARS-CoV-2 infection based on serial sero-surveys <br/ ><br>III. Estimate cumulative sero-conversion of SARS-CoV-2 infection over one year period <br/ ><br>IV. Estimate the sero-prevalence and annual sero conversion of Dengue and Chikungunya in a sub sample of the studyTimepoint: Sero-prevalence of COVID will be assessed at baseline, 4 months, 8 months and 12 months
- Secondary Outcome Measures
Name Time Method Secondary objectives <br/ ><br>I. Monitor the trend of SARS-CoV-2 transmission in the general population <br/ ><br>II. Determine the prevalence and incidence of SARS CoV2 sero-positivity among the members of the households with at least one seropositive individual (clustering of infection at household level) Determine the risk factors for SARS-CoV-2 infection <br/ ><br>III. Determine the duration of persistence of antibodies in individuals tested positive for SARS-CoV-2 infection <br/ ><br>Timepoint: Trend of infection and duration of persistence of antibodies will be monitored by the serial sero-surveys at 0,4,8 and 12 months. <br/ ><br>Incidence of symptomatic infections will be assessed via fortnightly phone calls.