A trial of G-CSF in septic shock excluding melioidosis.

Phase 4

Completed

• Conditions: Septic shock in adults not caused by melioidosis.; Inflammatory and Immune System - Other inflammatory or immune system disorders

• Registration Number: ACTRN12605000060640
• Lead Sponsor: Intensive care unit, Royal Darwin Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2005-08-01
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 164

Inclusion Criteria

Participants must fit the ACCP/SCCM Consensus Criteria for septic shock and other more recently agreed-upon non-invasive criteria. These criteria are; at least 2 signs of the presence of infection, cardiovascular failure (shock) and at least 1 sign of organ perfusion abnormality.

Exclusion Criteria

Culture confirmed melioidosis, febrile neutropaenia (following chemotherapy), known haematological malignancy, myelodysplasia or congenital neutropaenia, pregnancy, known hypersensitivity to G-CSF, known objection to participate in the trial, previous transplantation, previous participation in this trial, has received G-CSF in the past month, brain death, expected survival of less than 24 hours with active orders limiting treatment and myocardial infarction in the previous 24 hours.

Study & Design

• Study Type: Interventional
• Study Design: Not specified