Improving TB outcomes by modifying life-style behaviours through a behavioural intervention comprising motivational interviewing counselling strategy augmented with subsequent short text messaging
- Conditions
- TuberculosisInfections and Infestations
- Registration Number
- ISRCTN62728852
- Lead Sponsor
- South African Medical Research Council
- Brief Summary
2019 Protocol article in https://www.ncbi.nlm.nih.gov/pubmed/31349850 protocol (added 30/07/2019) 2022 Results article in https://pubmed.ncbi.nlm.nih.gov/35165113/ (added 21/06/2022)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 574
1. Adult patients (18 years or older) with drug-sensitive pulmonary TB (PTB)
2. Current smokers OR hazardous/harmful drinkers who are not alcohol dependent (AUDIT score = 8 for men or = 7 for women but <20)
3. Initiating TB treatment or on current TB treatment for less than 1 month (these include both new” and retreatment patients”)
4. Access to a functional cellphone
5. Understands one of the 4 languages used for the trial (Sesotho, Setswana, Zulu or English)
1. On TB treatment for more than one month
2. Alcohol dependent participants (AUDIT score more than or equal to 20) provided they are non-smokers
3. Extrapulmonary tuberculosis provided they don’t also have pulmonary tuberculosis
4. Drug resistance to one or more TB drugs at baseline.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Current primary outcome measure as of 15/10/2021:<br>TB treatment success rate measured according to treatment outcomes defined by the WHO and adopted in South Africa, at 6 to 9 months<br><br>_____<br><br>Previous primary outcome measure:<br>TB treatment success rate measured according to treatment outcomes defined by the WHO and adopted in South Africa, at 6 months
- Secondary Outcome Measures
Name Time Method