Increasing Physical Activity Through Personalised Motivational Messaging to Improve Cognitive Function in Lung Cancer Survivors
- Conditions
- Lung CancerPhysical InactivityNeoplasmsCognitive Impairment
- Interventions
- Behavioral: Regular message deliveryBehavioral: Chat-type support message delivery
- Registration Number
- NCT06003335
- Lead Sponsor
- The University of Hong Kong
- Brief Summary
Objectives: To examine the effectiveness of a personalised motivational messaging intervention for improving cognitive function in lung cancer survivors.
Hypothesis to be tested: Lung cancer survivors receiving personalised motivational messaging will have better cognitive function than usual care.
Design and subjects: A randomised controlled trial in 196 lung cancer survivors with cancer-related cognitive impairment.
Intervention: The intervention group will be equipped with a wearable activity tracker for 3 months and receive personalised motivational messages via instant messaging applications (e.g., WhatsApp) to promote physical exercise. The intervention will include 1) regular messages sent at preferred times and frequencies allowing participants to choose suggested physical activity goals, and 2) support via chat-type messaging such as goal setting, real-time counselling, and practical advice. The control group will receive a leaflet on cognitive impairment with reminder text messages for follow-up surveys.
Main outcome measures: Data will be conducted at baseline (T0), 3 months (T1; immediately after intervention delivery), and 6 months (T2; long-term follow up). Primary outcome will be cognitive function measured by HK-MoCA (objective) and Functional Assessment of Cancer Therapy-Cognitive Function (FACT-Cog) scale (subjective). Secondary outcomes are physical activity (IPAQ-SF), self-efficacy for exercise (SEE), psychological well-being (PHQ-4), and quality of life (EORTC QLQ-C30).
Data analysis: Intention-to-treat, post-trial qualitative (compliance with the intervention), and cost-effectiveness analyses will be conducted. We will follow the CONSORT-EHEALTH checklist.
Expected results: This trial will provide evidence on the effectiveness of the proposed intervention on improving cognitive function and increasing physical activity among lung cancer survivors.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- NOT_YET_RECRUITING
- Sex
- All
- Target Recruitment
- 120
- aged ≥ 18 years;
- diagnosed with stage I-III non-metastatic NSCLC cancer;
- completed primary treatment with curative intent (surgery, chemotherapy and/or radiation therapy) 6 months to 5 years prior to the baseline assessment with no recurrence or occurrence of additional cancers;
- identified as having mild cognitive impairment by the HK-MoCA 5-Min Protocol (≤ 7th age- and education-corrected percentile cut-off score);
- not engaged in regular exercise (defined as < 150 min of moderate-intensity exercise per week).
- inadequate reading and verbal Cantonese comprehension for the study activities;
- diagnosed with dementia;
- unable to use mobile phone text messaging applications (e.g., WhatsApp).
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description IG Regular message delivery The intervention group will receive personalised motivational messages (according to their physical activity levels and preferences screened during the baseline measurement) using instant messaging applications (e.g., WhatsApp). They will be equipped with a wearable activity tracker for 3 months to monitor their physical activity level. In accordance with the guidelines for mobile instant messageing development, we will develop a message content library and protocol for intervention delivery. IG Chat-type support message delivery The intervention group will receive personalised motivational messages (according to their physical activity levels and preferences screened during the baseline measurement) using instant messaging applications (e.g., WhatsApp). They will be equipped with a wearable activity tracker for 3 months to monitor their physical activity level. In accordance with the guidelines for mobile instant messageing development, we will develop a message content library and protocol for intervention delivery. CG 1 Regular message delivery Control group 1 will receive regular message delivery (as mentioned in the intervention) without personalised motivational messaging for better evaluation of the effect of personalized motivational messaging.
- Primary Outcome Measures
Name Time Method Functional Assessment of Cancer Therapy-Cognitive Function (FACT-Cog) at baseline (T0), 3 months (T1; immediately after intervention delivery), and 6 months (T2; long-term follow up) Primary outcome: subjective cognitve function
Hong Kong Montreal Cognitive Assessment (HK-MoCA) at baseline (T0), 3 months (T1; immediately after intervention delivery), and 6 months (T2; long-term follow up) Primary outcome: objective cognitve function
- Secondary Outcome Measures
Name Time Method Self-efficacy for exercise (SEE) at baseline (T0), 3 months (T1; immediately after intervention delivery), and 6 months (T2; long-term follow up) Self-efficacy for exercise
Patient Health Questionnaire 4 item (PHQ-4) at baseline (T0), 3 months (T1; immediately after intervention delivery), and 6 months (T2; long-term follow up) Psychological well-being
International Physical Activity Questionnaire-Short Form (IPAQ-SF) at baseline (T0), 3 months (T1; immediately after intervention delivery), and 6 months (T2; long-term follow up) Physical activity
European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30) at baseline (T0), 3 months (T1; immediately after intervention delivery), and 6 months (T2; long-term follow up) Quality of life
Trial Locations
- Locations (1)
School of Nursing, The University of Hong Kong
🇭🇰Hong Kong, Hong Kong