Sex differences in the effects of the combined exposure to cephalad fluid shift and mild hypercapnia on cerebral autoregulation
- Conditions
- Attenuated cerebral autoregulation due to microgravity
- Registration Number
- jRCT1030230757
- Lead Sponsor
- None
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 50
1)Persons who are within the age range of 18 to 35 at the time of consent. 2)Persons who have voluntarily consented to participate in this study, after being fully informed and understanding the study. 3)Persons who were determined to be healthy after a medical history and physical examination. 4)Women with menstrual cycles within the normal range (25 to 38 days). 5)Persons who can have a stable brain blood flow velocity waveform displayed by transcranial Doppler sonography in the supine position at rest.
1)Persons who have refused to participate in this study. 2Ppersons deemed ineligible by the principal investigator, such as those taller than 180 cm due to the specifications of the adjustable tilt electric bed. 3)Persons with or a history of cardiovascular diseases (including hypertension and arrhythmia), neurological disorders, respiratory diseases, autonomic nervous system dysfunction, severe systemic diseases, or anemia that has not been improved by treatment (as identified through medical history and physical examination). 4)Persons with a history of hypersensitivity to ultrasound transmission gel or other skin reactions (confirmed by medical interview) 5)Women taking oral contraceptives or other hormonal agents, those with irregular menstrual cycles (outside the normal range of 25 to 38 days), and pregnant women 6)Women whose menstrual cycles make it difficult to schedule experiments during the follicular phase
Study & Design
- Study Type
- Interventional
- Study Design
- single assignment
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method