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Promoting independence in bipolar disorder. Does cognitive remediation training of executive functioning lead to an improvement in wellbeing and personal goals of daily functioning?

Conditions
neurocognitive problems
planning and organization
10009841
10024450
Registration Number
NL-OMON50110
Lead Sponsor
GGZ Delfland (Delft)
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
Not specified
Target Recruitment
20
Inclusion Criteria

This study will be performed in an outpatient population of patients that are
in care of GGZ Delfland, an institute of specialized mental healthcare. Two
groups of 10 patients each will be formed, thus a total of 20 patients will
participate. Participants need to be of adult age (18-65 years old), mentally
competent, diagnosed with a bipolar I of bipolar II disorder, and need to be
stable for 3 months. At the moment of inclusion stability of symptomatology is
assessed by a score of <5 on the Altman Self-Rating Mania Rating Scale (Altman
et al., 1997) and a score of <16 on the Quick Inventory of Depressive Symptoms
(Rush et al., 2003); these are criteria also used in the study by Zyto et al
(2016). The clinical DSM diagnosis will be confirmed with the MINI-plus 5.0.0.
The Cognitive Failure Questionnaire (CFQ; Broadbent et al., 1982; Merckelbach
et al., 1996; Ponds, van Boxtel & Jolles, 2006) will be used to assess
perceived cognitive dysfunction in daily life. To participate the CFQ score
must be >43 (1 SD above mean).

Exclusion Criteria

An IQ < 80 as assessed by the Dutch Adult Reading Test (DART; Schmand and Van
Harskamp, 1992), mental incompetence, neurological problems, acquired brain
injury, electric convulsive therapy in the past 12 months, substance abuse in
the past 3 months, psychotic disorder, autism spectrum disorder, attention
deficit disorder, rapid cycling (multiple mood episodes within 12 months), and
neurocognitive disturbances due to severe posttraumatic stress disorder.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
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Secondary Outcome Measures
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