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Clinical Trials/NCT06481982
NCT06481982
Withdrawn
Not Applicable

Value of Advanced MRI Techniques in the Assessment of Endometriosis

University of Zurich1 site in 1 country300 target enrollmentMarch 1, 2026
ConditionsEndometriosis

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Endometriosis
Sponsor
University of Zurich
Enrollment
300
Locations
1
Primary Endpoint
Diagnostic Accuracy
Status
Withdrawn
Last Updated
7 months ago

Overview

Brief Summary

Endometriosis is a common gynaecological disease, mostly in women of reproductive age, with a prevalence of about 10 %, which is defined by the presence of endometrial-type tissue outside the uterine cavity. Endometriosis is usually limited to the abdominal and especially the pelvic cavity, extra-abdominal lesions are rare. Within the pelvis it shows a wide variety of locations predominantly affecting the ovaries and the uterus or the peritoneum, uterine ligaments and other pelvic structures. Traditionally, there are three major phenotypes of endometriosis: Ovarian endometrioma (OMA), superficial peritoneal endometriosis (SPE), and deep infiltrating endometriosis (DIE). A lesion is considered a DIE, if it shows infiltration deeper than 5 mm into the peritoneum. The ectopic endometrial implants may induce inflammatory processes, causing scar tissue formation, adhesions, and consequently pelvic anatomy distortion.

The prospective study aims to investigate the value of advanced MRI techniques to improve the assessment of pelvic endometriosis.

Registry
clinicaltrials.gov
Start Date
March 1, 2026
End Date
August 1, 2029
Last Updated
7 months ago
Study Type
Observational
Sex
Female

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patients who undergo clinically indicated MR imaging for endometriosis evaluation.

Exclusion Criteria

  • Non-MRI compatible devices/implants

Outcomes

Primary Outcomes

Diagnostic Accuracy

Time Frame: 5 years

Diagnostic accuracy of different MRI sequences in comparison to ultrasound assessment and/or laparoscopy as standard of reference.

Study Sites (1)

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