The preventive effect of medicine for osteoporosis on osteopenia in patients with Parkinson's disease: multicenter/ non-blind/ randomised/ exploratory clinical trial
Not Applicable
- Conditions
- Parkinson's disease
- Registration Number
- JPRN-UMIN000033285
- Lead Sponsor
- Department of Orthopaedic Surgery, Niigata University Medical and Dental Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
Not provided
Exclusion Criteria
1.patient corresponding to contraindication based on the attached document of the bone antiresorptive agents 2.patient with Hoen-Yahr grade 5 Parkinson's disease 3.patient who is considered not to be suited for this survey
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Primary evaluation item: change of the mean BMD in the prximal femur 2 years after initial treatment secondary evaluation item: 1.Change of the mean BMD in the proximal femur or lumbar spine 2 years after initial tramentt 2.Change of the bone absorption marker 3.Prevalence of new-onset fragile fracture 4.Correlation between QOL and spinal alignment 5.Longitudinal evaluation of BMD or bone resorption marker Safty assessment: Incidecne of adverse reactions for follow-up period
- Secondary Outcome Measures
Name Time Method