Effects of Bariatric Surgery in Swedish Obese Subjects
Not Applicable
Completed
- Conditions
- Obesity
- Interventions
- Procedure: Bariatric surgeryOther: Usual care
- Registration Number
- NCT01479452
- Lead Sponsor
- Göteborg University
- Brief Summary
The purpose of the Swedish Obese Subjects (SOS) study is to examine the long-term effects of bariatric surgery on overall mortality and obesity-related co-morbidities.
- Detailed Description
The Swedish Obese Subjects (SOS) study is a prospective non-randomized controlled intervention study designed to examine the long-term effects of bariatric surgery compared to usual care in obese subjects.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 4047
Inclusion Criteria
- Age 37-60 years and BMI ≥34 kg/m2 in men and ≥38 kg/m2 in women.
Exclusion Criteria
- Exclusion criteria of both groups were: earlier operation for gastric or duodenal ulcer; earlier bariatric surgery
- Gastric ulcer during the past 6 months; ongoing malignancy
- Active malignancy during the past 5 years
- Myocardial infarction during the past 6 months
- Bulimic eating pattern; drug or alcohol (>0·75 L 40% liquor per week or corresponding amount of ethanol) abuse
- Psychiatric or cooperative problems contraindicating bariatric surgery
- Other contraindicating conditions (such as continuous glucocorticoid or anti-inflammatory treatment).
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Bariatric surgery Bariatric surgery Bariatric surgery Controls Usual care Usual care
- Primary Outcome Measures
Name Time Method Overall mortality 10 years The SOS study was started in 1987 and effect of bariatric surgery on overall mortality (primary endpoint) was reported in 2007. Cut off date for the analysis was November 1, 2005.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
SOS secretariat, Vita Straket 15, Sahlgrenska University Hospital
🇸🇪Gothenburg, Sweden