A human study for investigating the effectiveness of Lactobacillus plantarum Q180 on control of triglyceride level
- Conditions
- Endocrine, nutritional and metabolic disease
- Registration Number
- KCT0002085
- Lead Sponsor
- Chong Kun Dang Bio
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- All
- Target Recruitment
- 80
1) Subject who voluntarily agrees to participate and sign in informed consent form
2) Man and postmenopausal women (45 years = Age )
3) Fasting triglyceride level =150mg/dL and <200mg/dL
1) Recommended Food Score > 36
2) BMI < 23kg/m2 or > 35 kg/m2
3) high-intensity exercise regularly (=10 hours/week)
4) Chronic smokers (=20cigarettes/day)
5) Alcoholics or drinking quantity: Alcohol 420g/week (soju about 7 bottles/week)
6) follwing disease or personal history
hyperlipidemia, diabetes mellitus, hypertension, liver complaint, enteropathy(including ulcerative colitis, lactose intolerance), renal disease, cardiovascular disease, cerebrovascular disease, pancreatitis, cancer, thyroid gland disease, dementia, Parkinson's disease, depressive disorder, anorexia nervosa/polyphagia, multiple sclerosis, Spinal cord injury
7) Volunteer who has taken follwing drug within 1.5 months or during study period : Lipid Lowering Agent(Ursodeoxycholic acid, statin etc), antidiabetics, antibiotics, durg affecting Intestinal Functions, hormone, oral contraception, durg affecting lipid metabolism.
8) Volunteer who has taken herbal medicine within 2 months.
9) Volunteer who has taken probiotics, prebiotics, dietary supplements that affect the body fat, lipid metabolism or intestinal health within 1 months.
10) Volunteer who are hypersensitivity to dietary supplement or ingredients contained in the supplement.
11) Volunteer who has been in clinical demonstration within 3 months.
12) pregnant woman or lactating women
13) Volunteer who judged incongruent by tester through clinical examination center.
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Lipid Levels and Related metabolic indicators
- Secondary Outcome Measures
Name Time Method gene expression relating lipid metabolism;Anthropometric Measurement ;bowel habits;intestinal health index (stool metabolome(monoenoic fatty acid, indole, phenol, biogenic amines), Harmful/beneficial bacteria identification)