Synergistic Effects of Green Tea Extract and Ginger Supplementation on Endurance Performance and Thermal Perception in Normal and Cold Environments: A Randomized, Double-Blind, Placebo-Controlled, Crossover Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 12
- 试验地点
- 1
- 主要终点
- Positive Peak Amplitude of Event-Related Potentials During Stroop - Congruent Trials
研究概览
简要总结
Objectives: The purpose of this study is to examine how meal timing in a one-meal-a-day (OMAD) regimen influences neurocognitive outcomes.
Methods: Twelve cognitively active participants (academics, students, software engineers) will complete three randomized OMAD conditions, consuming a standardized isocaloric meal at 08:00, 12:30, or 18:00. ERPs will be recorded during a computerized Stroop task to evaluate peak amplitudes and latencies under congruent and incongruent conditions. Resting-state EEG will be measured under eyes-open and eyes-closed conditions. Behavioral performance on the Stroop task, including reaction time and accuracy, will also be assessed.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 40 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Male, 20 to 45 years of age
- •Right-handed
- •Normal or corrected-to-normal vision
- •Cognitively active individuals (academic staff, graduate students, or software/algorithm engineers)
- •Regular sleep-wake schedule during the week preceding the experiment
- •Ability to abstain from caffeine, alcohol, or psychoactive substances for at least 24 hours prior to each test session
- •Body mass index between 18.5 and 30 kg/m²
排除标准
- •History of neurological, psychiatric, metabolic, or sleep disorders
- •Current use of medications that affect the central nervous system
- •Shift work or irregular sleep patterns (verified by sleep diary)
- •Prior experience with one-meal-a-day dietary routines
- •Body mass index below 18.5 or above 30 kg/m²
研究组 & 干预措施
Single Group (Crossover)
Arm Title: Morning Meal (08:00) Arm Type: Experimental Intervention: Other: One-meal-a-day (OMAD) Arm Description: Participants consume a single standardized isocaloric meal at 08:00. Neurocognitive outcomes (ERP, resting-state EEG, Stroop performance) are assessed during morning (before meal) and afternoon (approximately 6 hours post-meal) sessions.
Arm Title: Midday Meal (12:30) Arm Type: Experimental Intervention: Other: One-meal-a-day (OMAD) Arm Description: Participants consume a single standardized isocaloric meal at 12:30. Neurocognitive outcomes (ERP, resting-state EEG, Stroop performance) are assessed during morning (before meal) and afternoon (approximately 6 hours post-meal) sessions.
Arm Title: Evening Meal (18:00) Arm Type: Experimental Intervention: Other: One-meal-a-day (OMAD) Arm Description: Participants consume a single standardized isocaloric meal at 18:00. Neurocognitive outcomes (ERP, resting-state EEG, Stroop performance) are assessed during morning (before mea
干预措施: one-meal-a-day (OMAD) (Other)
结局指标
主要结局
Positive Peak Amplitude of Event-Related Potentials During Stroop - Congruent Trials
时间窗: Day 1 Morning session (09:30-11:00, pre-meal) and Day 1 Afternoon session (14:30-16:00, ~6 hours post-meal). Each participant completes three separate test days (morning, midday, evening feeding), ≥48 hours apart.
Maximum voltage deflection (µV) within 250-450 ms after stimulus onset at CP1, CP2, Pz, P3, O1, and O2 electrodes, recorded during congruent Stroop trials using a 32-channel EEG system.
Latency of Positive Peak of Event-Related Potentials During Stroop - Congruent Trials
时间窗: Day 1 Morning session (09:30-11:00, pre-meal) and Day 1 Afternoon session (14:30-16:00, ~6 hours post-meal). Each participant completes three separate test days (morning, midday, evening feeding), ≥48 hours apart.
Time point (ms) of maximum positive deflection within 250-450 ms after stimulus onset at CP1, CP2, Pz, P3, O1, and O2 electrodes.
次要结局
- Resting-State EEG Absolute Power (Eyes-Open and Eyes-Closed)(Day 1 Morning session (09:30-11:00, pre-meal) and Day 1 Afternoon session (14:30-16:00, ~6 hours post-meal). Each participant completes three separate test days (morning, midday, evening feeding), ≥48 hours apart.)
研究者
Süleyman Ulupınar
Associate Professor of Exercise Physiology
Erzurum Technical University