Neurocognitive Effects of Meal Timing in a One-Meal-a-Day Regimen

Not Applicable

Completed

• Conditions: Fasting State; Cognitive Abilities

• Registration Number: NCT07181057
• Lead Sponsor: Erzurum Technical University

Brief Summary

Objectives: The purpose of this study is to examine how meal timing in a one-meal-a-day (OMAD) regimen influences neurocognitive outcomes.

Methods: Twelve cognitively active participants (academics, students, software engineers) will complete three randomized OMAD conditions, consuming a standardized isocaloric meal at 08:00, 12:30, or 18:00. ERPs will be recorded during a computerized Stroop task to evaluate peak amplitudes and latencies under congruent and incongruent conditions. Resting-state EEG will be measured under eyes-open and eyes-closed conditions. Behavioral performance on the Stroop task, including reaction time and accuracy, will also be assessed.

Detailed Description

Not available

Study Timeline

• Study Start: 2025-03-01
• Primary Completion: 2025-05-01
• Study Completion: 2025-05-15
• Status Verified: 2025-08
• Study First Submitted: 2025-08-25
• Study First Submitted QC: 2025-09-11
• Last Update Submitted: 2025-09-11
• Study First Posted: 2025-09-18
• Last Update Posted: 2025-09-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 12

Inclusion Criteria

Male, 20 to 45 years of age

Right-handed

Normal or corrected-to-normal vision

Cognitively active individuals (academic staff, graduate students, or software/algorithm engineers)

Regular sleep-wake schedule during the week preceding the experiment

Ability to abstain from caffeine, alcohol, or psychoactive substances for at least 24 hours prior to each test session

Body mass index between 18.5 and 30 kg/m²

Exclusion Criteria

History of neurological, psychiatric, metabolic, or sleep disorders

Current use of medications that affect the central nervous system

Shift work or irregular sleep patterns (verified by sleep diary)

Prior experience with one-meal-a-day dietary routines

Body mass index below 18.5 or above 30 kg/m²

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Positive Peak Amplitude of Event-Related Potentials During Stroop - Congruent Trials	Day 1 Morning session (09:30-11:00, pre-meal) and Day 1 Afternoon session (14:30-16:00, ~6 hours post-meal). Each participant completes three separate test days (morning, midday, evening feeding), ≥48 hours apart.	Maximum voltage deflection (µV) within 250-450 ms after stimulus onset at CP1, CP2, Pz, P3, O1, and O2 electrodes, recorded during congruent Stroop trials using a 32-channel EEG system.
Latency of Positive Peak of Event-Related Potentials During Stroop - Congruent Trials	Day 1 Morning session (09:30-11:00, pre-meal) and Day 1 Afternoon session (14:30-16:00, ~6 hours post-meal). Each participant completes three separate test days (morning, midday, evening feeding), ≥48 hours apart.	Time point (ms) of maximum positive deflection within 250-450 ms after stimulus onset at CP1, CP2, Pz, P3, O1, and O2 electrodes.

Secondary Outcome Measures

Name	Time	Method
Resting-State EEG Absolute Power (Eyes-Open and Eyes-Closed)	Day 1 Morning session (09:30-11:00, pre-meal) and Day 1 Afternoon session (14:30-16:00, ~6 hours post-meal). Each participant completes three separate test days (morning, midday, evening feeding), ≥48 hours apart.	Broadband spectral power (µV²) recorded at CP1, CP2, Pz, P3, O1, and O2 electrodes during standardized eyes-open and eyes-closed resting-state EEG.

Trial Locations

Locations (1)

Erzurum Technical University Sport Sciences Faculty; Erzurum, Erzurum, Turkey (Türkiye)