Effects of electrical stimulation of the quadriceps muscle strength and walking capacities in patients with chronic kidney disease on hemodialysis

Phase 1

Recruiting

• Conditions: Diseases of the genitourinary system.Renal Insufficiency, Chronic.Renal Dialysis.End-stage renal disease.; C12.777.419.780.750; E02.870.300; N18.0

• Registration Number: RBR-6wvb5c
• Lead Sponsor: niversidade do Estado de Santa Catarina

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-03-01
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Patients with CKD diagnostic who are on dialysis regularly for at least 6 months, stable and under medical supervision; patients without: uncontrolled hypertension, recent ischemic heart disease (3 months or less), unstable angina and severe cardiac arrhythmias; patients without diseases that limit the electrical stimulation protocol (respiratory, orthopedic and / or neurological); patients who do not do any form of physical training or who have been held for more than six months.

Exclusion Criteria

Inability to perform any of the study assessments (lack of understanding or collaboration); recent decompensation of the clinical picture with or without hospitalization; presence of chronic obstructive pulmonary disease (COPD or emphysema), musculoskeletal diseases that impede the realization of assessments and training protocol, uncontrolled hypertension, recent ischemic heart disease (3 months or less), unstable angina and severe cardiac arrhythmias; abnormal sensitivity in the lower limbs.

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Peripheral muscle strength: increased quadriceps strength evaluated by the Isokinetic Biodex System 4 Pro in isometric mode. The highest peak extensor torque is recorded compared before and after training.<br><br>Six-minute walk test: will be used to evaluate submaximal exercise capacity and will be held in accordance with the recommendations of the American Thoracic Society (Holland et al, 2014.). The greater distance between the two tests will be used for the analysis, this being compared to pre and after training. The reference values are those described by Britto et al., 2013 and an increase of 25 meters after the training will be considered a clinically important improvement.