Relationship between skeletal muscle mass, abdominal obesity parameters and disability in chronic low back pain
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Appendicular skeletal muscle mass index, axial skeletal muscle mass, visceral fat area, subcutaneous fat area
研究概览
简要总结
This study adopts a cross-sectional design to investigate the associations between Appendicular Skeletal Muscle Mass Index (ASMI), Axial Skeletal Muscle Mass (AxSM), abdominal obesity parameters (visceral and subcutaneous fat areas), and disability in individuals with Chronic Low Back Pain (CLBP) compared to healthy controls. Participants with the CLBP group comprising adults aged 18–65 diagnosed with CLBP persisting for more than 3 months, while healthy controls will be matched for age, sex, and BMI, with no history of back pain. Exclusion criteria include the presence of other spinal pathologies, systemic conditions, recent surgeries, or pregnancy. A body composition analyzer will be used to measure ASMI, AxSM, and abdominal fat areas, while the Roland-Morris Disability Questionnaire (RMDQ) will assess disability. Statistical analysis will examine these variables, including gender-specific differences and comparisons between sarcopenic and non-sarcopenic individuals within the CLBP group. The study will adhere to ethical standards, securing informed consent from all participants and ensuring confidentiality throughout.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 40.00 Year(s) 至 70.00 Year(s)(—)
- 性别
- All
入选标准
- •Diagnosed with chronic low back pain.
排除标准
- •Recent surgery or trauma Systemic inflammatory diseases.
结局指标
主要结局
Appendicular skeletal muscle mass index, axial skeletal muscle mass, visceral fat area, subcutaneous fat area
时间窗: Baseline
次要结局
- Roland Morris Disability Questionnaire, Pain Intensity, Range of Motion, Muscle endurance, Physical performance test(Baseline)
研究者
Ayyappan S
Sri Ramachandra Institute of Higher Education and Research
