跳至主要内容
临床试验/CTRI/2025/02/080231
CTRI/2025/02/080231尚未招募不适用

Relationship between skeletal muscle mass, abdominal obesity parameters and disability in chronic low back pain

Sri Ramachandra Institute of Higher Education and Research1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2025年2月15日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
100
试验地点
1
主要终点
Appendicular skeletal muscle mass index, axial skeletal muscle mass, visceral fat area, subcutaneous fat area

研究概览

简要总结

This study adopts a cross-sectional design to investigate the associations between Appendicular Skeletal Muscle Mass Index (ASMI), Axial Skeletal Muscle Mass (AxSM), abdominal obesity parameters (visceral and subcutaneous fat areas), and disability in individuals with Chronic Low Back Pain (CLBP) compared to healthy controls. Participants with the CLBP group comprising adults aged 18–65 diagnosed with CLBP persisting for more than 3 months, while healthy controls will be matched for age, sex, and BMI, with no history of back pain. Exclusion criteria include the presence of other spinal pathologies, systemic conditions, recent surgeries, or pregnancy. A body composition analyzer will be used to measure ASMI, AxSM, and abdominal fat areas, while the Roland-Morris Disability Questionnaire (RMDQ) will assess disability. Statistical analysis will examine these variables, including gender-specific differences and comparisons between sarcopenic and non-sarcopenic individuals within the CLBP group. The study will adhere to ethical standards, securing informed consent from all participants and ensuring confidentiality throughout.

研究设计

研究类型
Observational

入排标准

年龄范围
40.00 Year(s) 至 70.00 Year(s)(—)
性别
All

入选标准

  • Diagnosed with chronic low back pain.

排除标准

  • Recent surgery or trauma Systemic inflammatory diseases.

结局指标

主要结局

Appendicular skeletal muscle mass index, axial skeletal muscle mass, visceral fat area, subcutaneous fat area

时间窗: Baseline

次要结局

  • Roland Morris Disability Questionnaire, Pain Intensity, Range of Motion, Muscle endurance, Physical performance test(Baseline)

研究者

申办方类型
Research institution and hospital
责任方
Principal Investigator
主要研究者

Ayyappan S

Sri Ramachandra Institute of Higher Education and Research

研究点 (1)

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