Effectivness of core exercise training in patients diagnosed with knee osteoarthritis - A randomized controlled trial

Not yet recruiting

Brief Summary: Knee osteoarthritis (OA) is a prevalent condition that leads to chronic disability in older adults. Around 80% of people with OA over the age of 60 have restricted movement, and 25% have trouble completing daily tasks. In India, up to 20% of people who have knee pain and signs of OA document being unable to perform everyday tasks. Evidence from previous studies states that the strength of hip and core musculature has a direct effect on knee joint loading, which in turn leads to disease progression. Therefore. it is proposed that the current study examine the efficacy of targeted core-specific strengthening exercises in conjunction with a routine rehabilitation regimen for knee OA, and evaluate its effectiveness on pain, patient-reported functional outcomes, physical function tests, knee strength, core endurance and correlate its impact on cartilage health and disease severity. Patients with knee OA, who meet the inclusion criteria will be recruited and randomly allocated into intervention and control groups. Clinical assessments including outcome measures - VAS, patient-reported outcomes, physical function tests, and muscle strength will be assessed on baseline, 4 weeks, 8 weeks and 12 weeks. Diagnostic assessments including Xray and USG will be done at baseline and 12 weeks. Following 12 weeks, the effect of the intervention will be compared between groups and the results will be reported.

Recruitment & Eligibility

Inclusion Criteria

Patients diagnosed with Kellgren Lawrence Grades 1- 3 of Knee OA.

Exclusion Criteria

Patients with severe knee OA, in whom knee replacement is indicated.
Patients with a history of hip OA, lower limb joint replacement, inflammatory arthritis, spine surgery, lower limb surgery, or corticoid injection within the past three months.
Patients with a diagnosis of knee OA whose clinical evaluation by the physical therapist at baseline was not consistent with knee OA based on age, history, and physical examination, or those with a diagnosis of other conditions such as knee sprain.

Primary Outcome Measures

Name	Time	Method
Visual Analog Scale	The above mentioned outcome measures will be taken at Baseline 4 weeks 8 weeks & 12 weeks
Physical Function Test KOOS	The above mentioned outcome measures will be taken at Baseline 4 weeks 8 weeks & 12 weeks
30second sit to stand	The above mentioned outcome measures will be taken at Baseline 4 weeks 8 weeks & 12 weeks
40 m fast-paced walking test	The above mentioned outcome measures will be taken at Baseline 4 weeks 8 weeks & 12 weeks
Stair Climb Test	The above mentioned outcome measures will be taken at Baseline 4 weeks 8 weeks & 12 weeks
Timed Up & Go Test	The above mentioned outcome measures will be taken at Baseline 4 weeks 8 weeks & 12 weeks

Secondary Outcome Measures

Name	Time	Method
Muscle strength, X-ray , USG	Baseline, 12 weeks

Locations (1): Kasturba Medical College, Hospitals
🇮🇳
Kannada, KARNATAKA, India
Kasturba Medical College, Hospitals
🇮🇳Kannada, KARNATAKA, India
Tina Thomas Dias
Principal investigator
8310324823
tina.mchpmlr2022@learner.manipal.edu