Impact of Covid-19 in the Emergency Department

Completed

• Conditions: COVID-19

• Registration Number: NCT05150821
• Lead Sponsor: Dr. Panagiota Manava

Brief Summary

To investigate the effects of lockdown in the Emergency Department in a tertiary health care hospital, Nuremberg, Germany.

Detailed Description

To investigate the effect of the first lockdown caused by the pandemic of Covid-19 in a tertiary health care hospital. Klinikum Nuremberg is one of the largest tertiary health care hospitals in Germany with two locations in Nuremberg. In the north department, around 150 outcome patients visit the Emergency Department every day.

During the pandemic in 2020 the capacities of the hospitals were saved for the patients with Covid-19. A decrease of patients presented in the ED was noticed. Controlling system and patient management provided the number of cases and correlated with the same period of time one year ago, before the pandemic.

For the classification of severity of diseases, different clinical diseases with severity scores were analyzed. Following diseases and scores were evaluated:

Pancreatitis -- \> ranson score; ACS (acute coronary syndrome) --\> Grace-Score; Pulmonary Embolism -- \> sPESI (simplified Pulmonary Embolism Severity Index); Diverticulitis --\> CDD (Classification of Diverticular Disease); Pneumonia -\> crb65 (Confusion- Respiratory rate- Blood pressure- age ≥ 65 years);

Study Timeline

• Study Start: 2020-09-01
• Study First Submitted: 2021-12-07
• Study First Submitted QC: 2021-12-08
• Study First Posted: 2021-12-09
• Primary Completion: 2023-07-01
• Study Completion: 2023-07-01
• Status Verified: 2023-08
• Last Update Submitted: 2023-08-24
• Last Update Posted: 2023-08-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 599

Inclusion Criteria

Only patients who presented in the ED.

Exclusion Criteria

none

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
CDD	through study completion, an average of 1 year	clinical severity index of diverticulitis. Min 0 - max. 4
Grace-Score	through study completion, an average of 1 year	clinical severity index of ACS. Estimates admission untill 6 month mortality for patients with acute coronary syndrome. 108 points: low risk. Over 141-372 points: high risk.
ranson score	through study completion, an average of 1 year	clinical severity index of pancreatitis. Estimates mortality of patients with pancreatitis, based on initial and 48-hour lab values. Min. 0 - Max. 11 points.
sPESI	through study completion, an average of 1 year	clinical severity index of pulmonary embolism. Predicts 30-day outcome of patients with pulmonary embolism. Min 0 points- max. 6 points
crb65	through study completion, an average of 1 year	The CRB-65-score is a clinical score that is used to estimate the severity of community-acquired pneumonias. The score corresponds to the statistical probability of patients dying because of pneumonia. Min 0 points - highest score 4 points.

Trial Locations

Locations (1)

Institute of Radiology and Nuclear Medicine; 🇩🇪 Nuremberg, Bavaria, Germany