NCT04650139
Recruiting
Not Applicable
Coronary Interventions Ulm - Coronary Chronic Total Occlusions
University Hospital Ulm1 site in 1 country500 target enrollmentJanuary 1, 2014
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Chronic Total Occlusion of Coronary Artery
- Sponsor
- University Hospital Ulm
- Enrollment
- 500
- Locations
- 1
- Primary Endpoint
- MACE
- Status
- Recruiting
- Last Updated
- 5 years ago
Overview
Brief Summary
The aim of the proposed project is to provide the long-term results after a recanalization attempt of chronically occluded coronary arteries.
To investigate recanalization attempt of chronically occluded coronary arteries at the Ulm University Hospital. As shown, it is known that successful recanalization of a chronic occlusion is associated with a lower event rate (reduced mortality and the need for operative myocardial revascularization) compared to unsuccessful recanalization (drug therapy). The standard in the therapy of successfully recanalized chronic occlusions is the use of drug-releasing vascular supports.
Investigators
Bruno Correia
Investigator
University Hospital Ulm
Eligibility Criteria
Inclusion Criteria
- •Patients over 18 years
- •Coronary intervention in chronic coronary artery occlusion
- •Occlusion \> 3 months
- •Indication for PTCA or recanalization according to guidlines
- •Symptoms of the patient
- •Evidence of myocardial ischemia (stress ECG, scintigraphic
- •Methods, magnetic resonance imaging, stress echocardiography)
- •pathological intracoronary flow reserve, prognostic
Exclusion Criteria
- •No chronic occlusion,
- •Contraindication to anti-platelet therapy
- •Acetylsalicylic acid plus clopidogrel for at least 3 months such as e.g.
- •with florid gastrointestinal ulcer disease,
- •History of hemorrhagic stroke
- •or urgent non-postponable surgical intervention.
- •Basic disease with a life expectancy of less than 12 months (here as a rule
- •no indication for PTCA or reopening available)
Outcomes
Primary Outcomes
MACE
Time Frame: 1 year
major adverse cardiac event
Secondary Outcomes
- TLR(1 year)
Study Sites (1)
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