Intravenous amino acid therapy for kidney protection in pediatric patients undergoing cardiac surgery

we hypothesized that an infusion of amino acids commenced before exposure to CPB intraoperatively and continue for 72 hours postoperatively in pediatric population undergoing complex cardiac surgeries, may help maintain renal blood flow, thus ameliorating the ischemic and inflammatory injury that contributes towards the onset of cardiac surgery associated AKI. we conducted this study to test this hypothesis. patients were randomly allocated to standard care or to commence an infusion of amino acids after induction of anesthesia and before exposure to CPB intraoperatively and continued for 72 hours postoperatively